All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-39294134
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39294134 E340D
S
S
COVID-19
D
R
S
C
L
View
2 39294134 T76I
S
S
COVID-19
R
S
C
L
View
3 39294134 A155D
N
N
COVID-19
R
S
C
L
View
4 39294134 D402H
N
N
COVID-19
R
S
C
L
View
5 39294134 A173T
NSP5
ORF1a
COVID-19
D
R
S
C
L
View
6 39294134 G283C
NSP5
ORF1a
COVID-19
R
S
C
L
View
7 39294134 M165I
NSP5
ORF1a
COVID-19
R
S
C
L
View
8 39294134 T169I
NSP5
ORF1a
COVID-19
D
R
S
C
L
View
9 39294134 T295I
NSP4
ORF1a
COVID-19
R
S
C
L
View
10 39294134 N1369S
NSP3
ORF1a
COVID-19
R
S
C
L
View
11 39294134 R568C
NSP3
ORF1a
COVID-19
R
S
C
L
View
12 39294134 S454R
NSP3
ORF1a
COVID-19
R
S
C
L
View
13 39294134 V573I
NSP3
ORF1a
COVID-19
R
S
C
L
View
14 39294134 C464Y
NSP12
ORF1b
COVID-19
D
R
S
C
L
View
15 39294134 C799Y
NSP12
ORF1b
COVID-19
D
R
S
C
L
View
16 39294134 E136A
NSP12
ORF1b
COVID-19
R
S
C
L
View
17 39294134 E796K
NSP12
ORF1b
COVID-19
R
S
C
L
View
18 39294134 M794I
NSP12
ORF1b
COVID-19
D
R
S
C
L
View
19 39294134 Q444K
NSP12
ORF1b
COVID-19
R
S
C
L
View
20 39294134 T643I
NSP12
ORF1b
COVID-19
R
S
C
L
View
21 39294134 V166L
NSP12
ORF1b
COVID-19
R
S
C
L
View
22 39294134 V223I
NSP12
ORF1b
COVID-19
R
S
C
L
View
23 39294134 V792I
NSP12
ORF1b
COVID-19
D
R
S
C
L
View
24 39294134 V820G
NSP12
ORF1b
COVID-19
R
S
C
L
View
25 39294134 A188S
M
M
COVID-19
R
S
C
L
View
26 39294134 I76T
M
M
COVID-19
R
S
C
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.