All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-39339934
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39339934 N501Y
S
S
COVID-19
G
View
2 39339934 Q498R
S
S
COVID-19
G
I
View
3 39339934 S373P
S
S
COVID-19
G
View
4 39339934 S375F
S
S
COVID-19
G
View
5 39339934 N440K
RBD
S
COVID-19
G
View
6 39339934 V445P
RBD
S
COVID-19
G
View
7 39339934 Q493E
S
S
COVID-19
G
I
View
8 39339934 E493Q
S
S
COVID-19
G
View
9 39339934 Q93E
RBD
S
COVID-19
G
View
10 39339934 R346T
S
S
COVID-19
G
I
View
11 39339934 T376A
S
S
COVID-19
G
View
12 39339934 F456L
S
S
COVID-19
G
I
View
13 39339934 V1104L
S
S
COVID-19
G
View
14 39339934 L455S
RBD
S
COVID-19
G
I
View
15 39339934 T572I
S
S
COVID-19
G
I
View
16 39339934 S455F
RBD
S
COVID-19
G
View
17 39339934 S455L
RBD
S
COVID-19
G
View
18 39339934 S455P
RBD
S
COVID-19
G
View
19 39339934 A475V
S
S
COVID-19
G
I
View
20 39339934 L455F
S
S
COVID-19
G
I
View
21 39339934 L452R
S
S
COVID-19
G
View
22 39339934 K417N
S
S
COVID-19
G
I
View
23 39339934 A484K
RBD
S
COVID-19
G
View
24 39339934 D339H
RBD
S
COVID-19
G
View
25 39339934 483delV
RBD
S
COVID-19
G
View
26 39339934 F486P
RBD
S
COVID-19
G
I
View
27 39339934 G446S
RBD
S
COVID-19
G
View
28 39339934 I332V
RBD
S
COVID-19
G
View
29 39339934 K356T
RBD
S
COVID-19
G
View
30 39339934 L452W
RBD
S
COVID-19
G
View
31 39339934 N450D
RBD
S
COVID-19
G
View
32 39339934 N460K
RBD
S
COVID-19
G
View
33 39339934 N481K
RBD
S
COVID-19
G
View
34 39339934 R403K
RBD
S
COVID-19
G
View
35 39339934 R493Q
RBD
S
COVID-19
G
View
36 39339934 V445H
RBD
S
COVID-19
G
View
37 39339934 D405N
S
S
COVID-19
G
View
38 39339934 R408S
S
S
COVID-19
G
View
39 39339934 Q493Q
S
S
COVID-19
G
View
40 39339934 Q493R
S
S
COVID-19
G
View
41 39339934 Y453F
S
S
COVID-19
G
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.