All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-39388246
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39388246 K417N
S
S
COVID-19
G
View
2 39388246 R346T
S
S
COVID-19
G
View
3 39388246 K444T
S
S
COVID-19
G
View
4 39388246 F486S
S
S
COVID-19
G
View
5 39388246 G339H
S
S
COVID-19
G
I
View
6 39388246 H339D
S
S
COVID-19
G
View
7 39388246 L452R
S
S
COVID-19
G
View
8 39388246 Q493R
S
S
COVID-19
G
View
9 39388246 S371L
S
S
COVID-19
G
I
View
10 39388246 A484R
S
S
COVID-19
G
View
11 39388246 F490S
S
S
COVID-19
G
View
12 39388246 G446S
S
S
COVID-19
G
View
13 39388246 K444R
S
S
COVID-19
G
View
14 39388246 L452M
S
S
COVID-19
G
View
15 39388246 N450D
S
S
COVID-19
G
View
16 39388246 N460K
S
S
COVID-19
G
View
17 39388246 R493Q
S
S
COVID-19
G
View
18 39388246 G339D
S
S
COVID-19
G
I
View
19 39388246 D339G
S
S
COVID-19
G
View
20 39388246 D339H
S
S
COVID-19
G
View
21 39388246 R346K
S
S
COVID-19
G
View
22 39388246 D405N
S
S
COVID-19
G
View
23 39388246 L371F
S
S
COVID-19
G
View
24 39388246 N440K
S
S
COVID-19
I
View
25 39388246 P337L
S
S
COVID-19
I
View
26 39388246 R346S
S
S
COVID-19
I
View
27 39388246 S486P
S
S
COVID-19
G
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.