All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-39599801
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39599801 A264D
S
S
COVID-19
G
R
L
View
2 39599801 A570V
S
S
COVID-19
G
R
L
View
3 39599801 211delN
S
S
COVID-19
G
R
L
View
4 39599801 483delV
S
S
COVID-19
G
R
L
View
5 39599801 E554K
S
S
COVID-19
G
R
L
View
6 39599801 F157S
S
S
COVID-19
G
R
L
View
7 39599801 H245N
S
S
COVID-19
G
R
L
View
8 39599801 I332V
S
S
COVID-19
G
R
L
View
9 39599801 K356T
S
S
COVID-19
G
R
L
View
10 39599801 L212I
S
S
COVID-19
G
R
L
View
11 39599801 L216F
S
S
COVID-19
G
R
L
View
12 39599801 L452W
S
S
COVID-19
G
R
L
View
13 39599801 L455S
S
S
COVID-19
G
R
L
View
14 39599801 N450D
S
S
COVID-19
G
R
L
View
15 39599801 N481K
S
S
COVID-19
G
R
L
View
16 39599801 P1143L
S
S
COVID-19
G
R
L
View
17 39599801 P621S
S
S
COVID-19
G
R
L
View
18 39599801 P681R
S
S
COVID-19
G
R
L
View
19 39599801 R158G
S
S
COVID-19
G
R
L
View
20 39599801 R21T
S
S
COVID-19
G
R
L
View
21 39599801 R403K
S
S
COVID-19
G
R
L
View
22 39599801 S50L
S
S
COVID-19
G
R
L
View
23 39599801 S939F
S
S
COVID-19
G
R
L
View
24 39599801 V127F
S
S
COVID-19
G
R
L
View
25 39599801 V445H
S
S
COVID-19
G
R
L
View
26 39599801 D253G
S
S
COVID-19
G
R
L
View
27 39599801 F186I
S
S
COVID-19
G
R
L
View
28 39599801 P521S
S
S
COVID-19
G
R
L
View
29 39599801 T478R
S
S
COVID-19
G
R
L
View
30 39599801 A27S
S
S
COVID-19
G
R
L
View
31 39599801 D405N
S
S
COVID-19
G
R
L
View
32 39599801 D614G
S
S
COVID-19
G
R
L
View
33 39599801 D796Y
S
S
COVID-19
G
R
L
View
34 39599801 144delY
S
S
COVID-19
G
R
L
View
35 39599801 G142D
S
S
COVID-19
G
R
L
View
36 39599801 H655Y
S
S
COVID-19
G
R
L
View
37 39599801 K417N
S
S
COVID-19
G
R
L
View
38 39599801 N440K
S
S
COVID-19
G
R
L
View
39 39599801 N460K
S
S
COVID-19
G
R
L
View
40 39599801 N501Y
S
S
COVID-19
G
R
L
View
41 39599801 N679K
S
S
COVID-19
G
R
L
View
42 39599801 N764K
S
S
COVID-19
G
R
L
View
43 39599801 N969K
S
S
COVID-19
G
R
L
View
44 39599801 Q498R
S
S
COVID-19
G
R
L
View
45 39599801 Q954H
S
S
COVID-19
G
R
L
View
46 39599801 R408S
S
S
COVID-19
G
R
L
View
47 39599801 S371F
S
S
COVID-19
G
R
L
View
48 39599801 S373P
S
S
COVID-19
G
R
L
View
49 39599801 S375F
S
S
COVID-19
G
R
L
View
50 39599801 S477N
S
S
COVID-19
G
R
L
View
51 39599801 T19I
S
S
COVID-19
G
R
L
View
52 39599801 T376A
S
S
COVID-19
G
R
L
View
53 39599801 T478K
S
S
COVID-19
G
R
L
View
54 39599801 E484A
S
S
COVID-19
G
R
L
View
55 39599801 P681H
S
S
COVID-19
G
R
L
View
56 39599801 R346T
S
S
COVID-19
G
R
L
View
57 39599801 F486V
S
S
COVID-19
G
R
L
View
58 39599801 G339D
S
S
COVID-19
G
R
L
View
59 39599801 K444T
S
S
COVID-19
G
R
L
View
60 39599801 L452R
S
S
COVID-19
G
R
L
View
61 39599801 Y505H
S
S
COVID-19
G
R
L
View
62 39599801 F486P
S
S
COVID-19
G
R
L
View
63 39599801 G339H
S
S
COVID-19
G
R
L
View
64 39599801 G446S
S
S
COVID-19
G
R
L
View
65 39599801 F490S
S
S
COVID-19
G
R
L
View
66 39599801 G252V
S
S
COVID-19
G
R
L
View
67 39599801 H146Q
S
S
COVID-19
G
R
L
View
68 39599801 L368I
S
S
COVID-19
G
R
L
View
69 39599801 Q183E
S
S
COVID-19
G
R
L
View
70 39599801 V213E
S
S
COVID-19
G
R
L
View
71 39599801 V213G
S
S
COVID-19
G
R
L
View
72 39599801 V445P
S
S
COVID-19
G
R
L
View
73 39599801 V83A
S
S
COVID-19
G
R
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.