All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-39604601
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39604601 L116F
ORF7a
ORF7a
COVID-19
G
L
View
2 39604601 R385K
N
N
COVID-19
G
L
View
3 39604601 A222V
S
S
COVID-19
G
L
View
4 39604601 G158R
S
S
COVID-19
G
L
View
5 39604601 L452R
S
S
COVID-19
G
L
View
6 39604601 P681R
S
S
COVID-19
G
L
View
7 39604601 R158G
S
S
COVID-19
G
L
View
8 39604601 T478K
S
S
COVID-19
G
L
View
9 39604601 A1918V
ORF1b
ORF1b
COVID-19
G
L
View
10 39604601 H2285Y
ORF1b
ORF1b
COVID-19
G
L
View
11 39604601 T40I
ORF1b
ORF1b
COVID-19
G
L
View
12 39604601 A1306S
ORF1a
ORF1a
COVID-19
G
L
View
13 39604601 A3209V
ORF1a
ORF1a
COVID-19
G
L
View
14 39604601 L1640P
ORF1a
ORF1a
COVID-19
G
L
View
15 39604601 P2046L
ORF1a
ORF1a
COVID-19
G
L
View
16 39604601 P2887S
ORF1a
ORF1a
COVID-19
G
L
View
17 39604601 P309L
ORF1a
ORF1a
COVID-19
G
L
View
18 39604601 T3255I
ORF1a
ORF1a
COVID-19
G
L
View
19 39604601 T3646A
ORF1a
ORF1a
COVID-19
G
L
View
20 39604601 V3718A
ORF1a
ORF1a
COVID-19
G
L
View
21 39604601 G215C
N
N
COVID-19
G
L
View
22 39604601 L139F
N
N
COVID-19
G
L
View
23 39604601 P241L
ORF1a
ORF1a
COVID-19
G
L
View
24 39604601 I95T
S
S
COVID-19
G
L
View
25 39604601 A231Y
NSP3
ORF1a
COVID-19
G
L
View
26 39604601 H1467Y
NSP3
ORF1a
COVID-19
G
L
View
27 39604601 P3504L
ORF1a
ORF1a
COVID-19
G
L
View
28 39604601 A54S
ORF3a
ORF3a
COVID-19
G
L
View
29 39604601 D173G
ORF3a
ORF3a
COVID-19
G
L
View
30 39604601 R163C
NSP14
ORF1b
COVID-19
G
L
View
31 39604601 E484K
S
S
COVID-19
G
L
View
32 39604601 N501Y
S
S
COVID-19
G
L
View
33 39604601 H119R
ORF1b
ORF1b
COVID-19
G
L
View
34 39604601 M458I
ORF1a
ORF1a
COVID-19
G
L
View
35 39604601 E264G
NSP2
ORF1a
COVID-19
G
L
View
36 39604601 G142D
S
S
COVID-19
L
View
37 39604601 V48F
ORF3a
ORF3a
COVID-19
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.