All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-39720734
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39720734 D614G
S
S
COVID-19
G
View
2 39720734 D950N
S
S
COVID-19
G
View
3 39720734 G142D
S
S
COVID-19
G
View
4 39720734 L452R
S
S
COVID-19
G
View
5 39720734 P681R
S
S
COVID-19
G
View
6 39720734 R158G
S
S
COVID-19
G
View
7 39720734 T19R
S
S
COVID-19
G
View
8 39720734 T478K
S
S
COVID-19
G
View
9 39720734 N679K
S
S
COVID-19
G
View
10 39720734 P681H
S
S
COVID-19
G
View
11 39720734 G339D
S
S
COVID-19
G
View
12 39720734 G446S
S
S
COVID-19
G
View
13 39720734 N764K
S
S
COVID-19
G
View
14 39720734 S375F
S
S
COVID-19
G
View
15 39720734 Y145D
NTD
S
COVID-19
G
View
16 39720734 E484A
RBD
S
COVID-19
View
17 39720734 N501Y
RBD
S
COVID-19
View
18 39720734 Y453F
RBD
S
COVID-19
View
19 39720734 E484K
RBD
S
COVID-19
I
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.