All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-39774959
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39774959 F456L
S
S
COVID-19
G
View
2 39774959 R346T
S
S
COVID-19
G
View
3 39774959 A246D
S
S
COVID-19
G
View
4 39774959 E554K
S
S
COVID-19
G
View
5 39774959 H245N
S
S
COVID-19
G
I
View
6 39774959 K356T
S
S
COVID-19
G
View
7 39774959 N450D
S
S
COVID-19
G
View
8 39774959 V445H
S
S
COVID-19
G
View
9 39774959 A264D
S
S
COVID-19
I
View
10 39774959 F157L
S
S
COVID-19
I
View
11 39774959 F486P
S
S
COVID-19
View
12 39774959 G142D
S
S
COVID-19
I
View
13 39774959 I794N
S
S
COVID-19
View
14 39774959 L452R
S
S
COVID-19
View
15 39774959 L455F
S
S
COVID-19
View
16 39774959 N501Y
S
S
COVID-19
View
17 39774959 N679K
S
S
COVID-19
View
18 39774959 N969K
S
S
COVID-19
View
19 39774959 P681R
S
S
COVID-19
View
20 39774959 Q498R
S
S
COVID-19
View
21 39774959 Q954H
S
S
COVID-19
View
22 39774959 T19I
S
S
COVID-19
I
View
23 39774959 T19R
S
S
COVID-19
I
View
24 39774959 P13L
N
N
COVID-19
View
25 39774959 R203K
N
N
COVID-19
View
26 39774959 R203M
N
N
COVID-19
View
27 39774959 R32C
N
N
COVID-19
View
28 39774959 S106T
NSP6
ORF1a
COVID-19
View
29 39774959 T492I
NSP4
ORF1a
COVID-19
View
30 39774959 G671S
NSP12
ORF1b
COVID-19
View
31 39774959 Q677P
Furin cleavage site
S
COVID-19
View
32 39774959 S680P
Furin cleavage site
S
COVID-19
View
33 39774959 A520S COVID-19
View
34 39774959 A626S COVID-19
I
View
35 39774959 A879S COVID-19
I
View
36 39774959 D138Y COVID-19
I
View
37 39774959 F108L COVID-19
View
38 39774959 N439K COVID-19
I
View
39 39774959 W152L COVID-19
I
View
40 39774959 W152R COVID-19
I
View
41 39774959 N460K
S
S
COVID-19
G
View
42 39774959 T478K
S
S
COVID-19
G
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.