All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-39881253
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39881253 G446S
S
S
COVID-19
G
L
View
2 39881253 L452W
S
S
COVID-19
G
L
View
3 39881253 V445H
S
S
COVID-19
G
L
View
4 39881253 A22910G
S
S
COVID-19
L
View
5 39881253 A23013C
S
S
COVID-19
L
View
6 39881253 A23055G
S
S
COVID-19
L
View
7 39881253 A23063T
S
S
COVID-19
L
View
8 39881253 A23403G
S
S
COVID-19
L
View
9 39881253 C22916T
S
S
COVID-19
L
View
10 39881253 C22995A
S
S
COVID-19
L
View
11 39881253 C23525T
S
S
COVID-19
L
View
12 39881253 C23604A
S
S
COVID-19
L
View
13 39881253 D614G
S
S
COVID-19
L
View
14 39881253 E484A
S
S
COVID-19
L
View
15 39881253 F456L
S
S
COVID-19
L
View
16 39881253 F490S
S
S
COVID-19
L
View
17 39881253 G22813T
S
S
COVID-19
L
View
18 39881253 G22898A
S
S
COVID-19
L
View
19 39881253 G22899T
S
S
COVID-19
L
View
20 39881253 G22992A
S
S
COVID-19
L
View
21 39881253 G23012A
S
S
COVID-19
L
View
22 39881253 G23561A
S
S
COVID-19
L
View
23 39881253 G23587T
S
S
COVID-19
L
View
24 39881253 G446I
S
S
COVID-19
L
View
25 39881253 G614D
S
S
COVID-19
L
View
26 39881253 G667S
S
S
COVID-19
L
View
27 39881253 K417N
S
S
COVID-19
L
View
28 39881253 T22882G
S
S
COVID-19
L
View
29 39881253 T22896A
S
S
COVID-19
L
View
30 39881253 T22917G
S
S
COVID-19
L
View
31 39881253 T22942A
S
S
COVID-19
L
View
32 39881253 T23018G
S
S
COVID-19
L
View
33 39881253 T23075C
S
S
COVID-19
L
View
34 39881253 T23599G
S
S
COVID-19
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.