All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-40006937
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 40006937 G142D
S
S
COVID-19
G
S
L
View
2 40006937 H655Y
S
S
COVID-19
G
S
L
View
3 40006937 D950N
S
S
COVID-19
G
S
L
View
4 40006937 E156G
S
S
COVID-19
G
S
L
View
5 40006937 L452R
S
S
COVID-19
G
S
L
View
6 40006937 P681R
S
S
COVID-19
G
S
L
View
7 40006937 T19R
S
S
COVID-19
G
S
L
View
8 40006937 T478K
S
S
COVID-19
G
S
L
View
9 40006937 A1918V
ORF1b
ORF1b
COVID-19
G
S
L
View
10 40006937 G662S
ORF1b
ORF1b
COVID-19
G
S
L
View
11 40006937 P1000L
ORF1b
ORF1b
COVID-19
G
S
L
View
12 40006937 A1306S
ORF1a
ORF1a
COVID-19
G
S
L
View
13 40006937 A3209V
ORF1a
ORF1a
COVID-19
G
S
L
View
14 40006937 H2092Y
ORF1a
ORF1a
COVID-19
G
S
L
View
15 40006937 K261N
ORF1a
ORF1a
COVID-19
G
S
L
View
16 40006937 P1640L
ORF1a
ORF1a
COVID-19
G
S
L
View
17 40006937 P2287S
ORF1a
ORF1a
COVID-19
G
S
L
View
18 40006937 P309L
ORF1a
ORF1a
COVID-19
G
S
L
View
19 40006937 T3255I
ORF1a
ORF1a
COVID-19
G
S
L
View
20 40006937 T3646A
ORF1a
ORF1a
COVID-19
G
S
L
View
21 40006937 V2930L
ORF1a
ORF1a
COVID-19
G
S
L
View
22 40006937 V3718A
ORF1a
ORF1a
COVID-19
G
S
L
View
23 40006937 D377Y
N
N
COVID-19
G
S
L
View
24 40006937 D63G
N
N
COVID-19
G
S
L
View
25 40006937 G215C
N
N
COVID-19
G
S
L
View
26 40006937 M1X
N
N
COVID-19
G
S
L
View
27 40006937 R203M
N
N
COVID-19
G
S
L
View
28 40006937 D614G
S
S
COVID-19
G
S
L
View
29 40006937 T95I
S
S
COVID-19
G
S
L
View
30 40006937 P314L
ORF1b
ORF1b
COVID-19
G
S
L
View
31 40006937 L3606F
ORF1a
ORF1a
COVID-19
G
S
L
View
32 40006937 G204R COVID-19
G
S
L
View
33 40006937 A23403G
S
S
COVID-19
S
L
View
34 40006937 C23604G
S
S
COVID-19
S
L
View
35 40006937 T60A
ORF9b
ORF9b
COVID-19
S
L
View
36 40006937 C25469T
ORF3a
ORF3a
COVID-19
S
L
View
37 40006937 S26L
ORF3a
ORF3a
COVID-19
S
L
View
38 40006937 G15451A
ORF1b
ORF1b
COVID-19
S
L
View
39 40006937 C3037T
NSP3
ORF1a
COVID-19
S
L
View
40 40006937 C14408T
NSP12
ORF1b
COVID-19
S
L
View
41 40006937 I82T
M
M
COVID-19
S
L
View
42 40006937 T26767C
M
M
COVID-19
S
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.