All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Carcinoma, Hepatocellular-21108338

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	21108338	C135A	PreS2	S	Carcinoma, Hepatocellular	G C L	View
2	21108338	C135T	PreS2	S	Carcinoma, Hepatocellular	G C L	View
3	21108338	C1A	PreS2	S	Carcinoma, Hepatocellular	G C L	View
4	21108338	C1G	PreS2	S	Carcinoma, Hepatocellular	G C L	View
5	21108338	T105C	PreS2	S	Carcinoma, Hepatocellular	G C L	View
6	21108338	A1762T	BCP		Carcinoma, Hepatocellular	G C L	View
7	21108338	A2962G	PreS1	S	Carcinoma, Hepatocellular	G C L	View
8	21108338	C105T	PreS2	S	Carcinoma, Hepatocellular	G C L	View
9	21108338	G1764A	BCP		Carcinoma, Hepatocellular	G C L	View
10	21108338	T1753V	BCP		Carcinoma, Hepatocellular	G C L	View
11	21108338	C52A	PreS2	S	Carcinoma, Hepatocellular	G C L	View
12	21108338	C52T	PreS2	S	Carcinoma, Hepatocellular	G C L	View
13	21108338	A109C	PreS2	S	Carcinoma, Hepatocellular	G C L	View
14	21108338	A109T	PreS2	S	Carcinoma, Hepatocellular	G C L	View
15	21108338	A10C	PreS2	S	Carcinoma, Hepatocellular	G C L	View
16	21108338	A10T	PreS2	S	Carcinoma, Hepatocellular	G C L	View
17	21108338	A1652G	EnhII		Carcinoma, Hepatocellular	G C L	View
18	21108338	A1846T	PreC	C	Carcinoma, Hepatocellular	G C L	View
19	21108338	A3054C	PreS1	S	Carcinoma, Hepatocellular	G C L	View
20	21108338	A3054T	PreS1	S	Carcinoma, Hepatocellular	G C L	View
21	21108338	A3120C	PreS1	S	Carcinoma, Hepatocellular	G C L	View
22	21108338	A3120G	PreS1	S	Carcinoma, Hepatocellular	G C L	View
23	21108338	A3120T	PreS1	S	Carcinoma, Hepatocellular	G C L	View
24	21108338	A49G	PreS2	S	Carcinoma, Hepatocellular	G C L	View
25	21108338	A49T	PreS2	S	Carcinoma, Hepatocellular	G C L	View
26	21108338	A7C	PreS2	S	Carcinoma, Hepatocellular	G C L	View
27	21108338	C1653T	EnhII		Carcinoma, Hepatocellular	G C L	View
28	21108338	C1673T	EnhII		Carcinoma, Hepatocellular	G C L	View
29	21108338	C1730G	EnhII		Carcinoma, Hepatocellular	G C L	View
30	21108338	C1799G	BCP		Carcinoma, Hepatocellular	G C L	View
31	21108338	C2875A	PreS1	S	Carcinoma, Hepatocellular	G C L	View
32	21108338	C2875T	PreS1	S	Carcinoma, Hepatocellular	G C L	View
33	21108338	C2964A	PreS1	S	Carcinoma, Hepatocellular	G C L	View
34	21108338	C3026T	PreS1	S	Carcinoma, Hepatocellular	G C L	View
35	21108338	C3060A	PreS1	S	Carcinoma, Hepatocellular	G C L	View
36	21108338	C3060T	PreS1	S	Carcinoma, Hepatocellular	G C L	View
37	21108338	C3063G	PreS1	S	Carcinoma, Hepatocellular	G C L	View
38	21108338	C31A	PreS2	S	Carcinoma, Hepatocellular	G C L	View
39	21108338	C31T	PreS2	S	Carcinoma, Hepatocellular	G C L	View
40	21108338	G1727A	EnhII		Carcinoma, Hepatocellular	G C L	View
41	21108338	G1727T	EnhII		Carcinoma, Hepatocellular	G C L	View
42	21108338	G1896A	PreC	C	Carcinoma, Hepatocellular	G C L	View
43	21108338	G2946A	PreS1	S	Carcinoma, Hepatocellular	G C L	View
44	21108338	G2946C	PreS1	S	Carcinoma, Hepatocellular	G C L	View
45	21108338	G3191A	PreS1	S	Carcinoma, Hepatocellular	G C L	View
46	21108338	G3191C	PreS1	S	Carcinoma, Hepatocellular	G C L	View
47	21108338	T1674G	EnhII		Carcinoma, Hepatocellular	G C L	View
48	21108338	T1719G	EnhII		Carcinoma, Hepatocellular	G C L	View
49	21108338	T2857C	PreS1	S	Carcinoma, Hepatocellular	G C L	View
50	21108338	T3066A	PreS1	S	Carcinoma, Hepatocellular	G C L	View
51	21108338	T3066C	PreS1	S	Carcinoma, Hepatocellular	G C L	View
52	21108338	T53C	PreS2	S	Carcinoma, Hepatocellular	G C L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.