All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Carcinoma, Hepatocellular-24637457
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 24637457 G50R
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
2 24637457 T36A
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
3 24637457 G1896A
PreC
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
4 24637457 F8L
S
S
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
5 24637457 L209V
S
S
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
6 24637457 S207N
S
S
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
7 24637457 S210M
S
S
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
8 24637457 T118V
S
S
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
9 24637457 A21S
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
10 24637457 A223S
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
11 24637457 A329P
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
12 24637457 A342C
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
13 24637457 D263E
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
14 24637457 D7A
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
15 24637457 F122L
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
16 24637457 H9Y
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
17 24637457 I253V
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
18 24637457 L308A
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
19 24637457 L336M
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
20 24637457 M129L
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
21 24637457 N248H
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
22 24637457 N337F
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
23 24637457 Q344P
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
24 24637457 V163I
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
25 24637457 V341S
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
26 24637457 Y135S
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
27 24637457 Y305A
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
28 24637457 Y335N
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
29 24637457 Y339T
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
30 24637457 Y54H
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
31 24637457 A144H
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
32 24637457 A31S
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
33 24637457 E126R
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
34 24637457 L98C
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
35 24637457 P145Q
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
36 24637457 Q87H
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
37 24637457 R32G
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
38 24637457 S11P
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
39 24637457 S33P
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
40 24637457 V133Y
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
41 24637457 V37L
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
42 24637457 A160S
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
43 24637457 C77G
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
44 24637457 D31A
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
45 24637457 M30L
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
46 24637457 P159Q
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
47 24637457 P34H
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
48 24637457 Q211H
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
49 24637457 S150V
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
50 24637457 T120N
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
51 24637457 T138Q
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
52 24637457 Y161I
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
53 24637457 A181G
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
D
G
R
S
C
L
 View
54 24637457 I233V
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
D
G
R
S
C
L
 View
55 24637457 L180X
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
D
G
R
S
C
L
 View
56 24637457 M204V
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
D
G
R
S
C
L
 View
57 24637457 M250V
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
D
G
R
S
C
L
 View
58 24637457 N236I
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
D
G
R
S
C
L
 View
59 24637457 Q215S
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
D
G
R
S
C
L
 View
60 24637457 S202I
RT
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
D
G
R
S
C
L
 View
61 24637457 D45L
P
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
62 24637457 E64N
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
63 24637457 F19X
S
S
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
64 24637457 I169N
P
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
D
G
R
S
C
L
 View
65 24637457 L30F
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
66 24637457 L80X
P
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
D
G
R
S
C
L
 View
67 24637457 M103D
X
X
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
68 24637457 S74X
P
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
69 24637457 T49S
C
C
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
70 24637457 T70X
P
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
71 24637457 V173L
P
P
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
D
G
R
S
C
L
 View
72 24637457 V47G
S
S
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
R
S
C
L
 View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.