All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Carcinoma, Hepatocellular-27486882

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	27486882	F19L	S	S	Carcinoma, Hepatocellular	G R I C L	View
2	27486882	G76A	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
3	27486882	I273L	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
4	27486882	L54P	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
5	27486882	N222T	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
6	27486882	P124K	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
7	27486882	P24L	S	S	Carcinoma, Hepatocellular	G R I C L	View
8	27486882	P41H	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
9	27486882	P66L	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
10	27486882	Q129H	S	S	Carcinoma, Hepatocellular	G R I C L	View
11	27486882	S59F	S	S	Carcinoma, Hepatocellular	G R I C L	View
12	27486882	T131I	S	S	Carcinoma, Hepatocellular	G R I C L	View
13	27486882	T40S	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
14	27486882	N103D	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
15	27486882	G44G	S	S	Carcinoma, Hepatocellular	G R I C L	View
16	27486882	F75S	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
17	27486882	G44E	S	S	Carcinoma, Hepatocellular	G R I C L	View
18	27486882	G91A	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
19	27486882	G99E	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
20	27486882	H114T	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
21	27486882	I110L	S	S	Carcinoma, Hepatocellular	G R I C L	View
22	27486882	I147T	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
23	27486882	I165L	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
24	27486882	I255T	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
25	27486882	I92T	S	S	Carcinoma, Hepatocellular	G R I C L	View
26	27486882	N59T	S	S	Carcinoma, Hepatocellular	G R I C L	View
27	27486882	Q184H	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
28	27486882	S98T	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
29	27486882	T114I	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
30	27486882	T119P	PreS1	S	Carcinoma, Hepatocellular	G R C L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.