All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Carcinoma, Hepatocellular-27727182

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	27727182	A60E	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
2	27727182	A60V	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
3	27727182	C1766T	X	X	Carcinoma, Hepatocellular	G R C L	View
4	27727182	C3026W	PreS1	S	Carcinoma, Hepatocellular	G R C L	View
5	27727182	F132Y	X	X	Carcinoma, Hepatocellular	G R C L	View
6	27727182	F22L	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
7	27727182	G1053A	P	P	Carcinoma, Hepatocellular	G R C L	View
8	27727182	G1229A	P	P	Carcinoma, Hepatocellular	G R C L	View
9	27727182	G1899A	PreC	C	Carcinoma, Hepatocellular	G R C L	View
10	27727182	G29D	PreC	C	Carcinoma, Hepatocellular	G R C L	View
11	27727182	H94Y	X	X	Carcinoma, Hepatocellular	G R C L	View
12	27727182	I126S	S	S	Carcinoma, Hepatocellular	G R C L	View
13	27727182	I126T	S	S	Carcinoma, Hepatocellular	G R C L	View
14	27727182	I127N	X	X	Carcinoma, Hepatocellular	G R C L	View
15	27727182	I127S	X	X	Carcinoma, Hepatocellular	G R C L	View
16	27727182	I127T	X	X	Carcinoma, Hepatocellular	G R C L	View
17	27727182	I97F	C	C	Carcinoma, Hepatocellular	G R C L	View
18	27727182	I97L	C	C	Carcinoma, Hepatocellular	G R C L	View
19	27727182	K130M	X	X	Carcinoma, Hepatocellular	G R C L	View
20	27727182	M1I	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
21	27727182	M1T	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
22	27727182	M1V	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
23	27727182	P130A	C	C	Carcinoma, Hepatocellular	G R C L	View
24	27727182	P130T	C	C	Carcinoma, Hepatocellular	G R C L	View
25	27727182	R713Q	P	P	Carcinoma, Hepatocellular	G R C L	View
26	27727182	S49T	C	C	Carcinoma, Hepatocellular	G R C L	View
27	27727182	S87G	C	C	Carcinoma, Hepatocellular	G R C L	View
28	27727182	T1768A	X	X	Carcinoma, Hepatocellular	G R C L	View
29	27727182	T31C	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
30	27727182	T531S	S	S	Carcinoma, Hepatocellular	G R C L	View
31	27727182	T53C	PreS2	S	Carcinoma, Hepatocellular	G R C L	View
32	27727182	V131I	X	X	Carcinoma, Hepatocellular	G R C L	View
33	27727182	V13A	C	C	Carcinoma, Hepatocellular	G R C L	View
34	27727182	W28X	PreC	C	Carcinoma, Hepatocellular	G R C L	View
35	27727182	A1762T	X	X	Carcinoma, Hepatocellular	G R C L	View
36	27727182	A2159G	C	C	Carcinoma, Hepatocellular	G R C L	View
37	27727182	A2189Y	C	C	Carcinoma, Hepatocellular	G R C L	View
38	27727182	C1653T	X	X	Carcinoma, Hepatocellular	G R C L	View
39	27727182	C2288R	C	C	Carcinoma, Hepatocellular	G R C L	View
40	27727182	G1613A	X	X	Carcinoma, Hepatocellular	G R C L	View
41	27727182	G1764A	X	X	Carcinoma, Hepatocellular	G R C L	View
42	27727182	G2203W	C	C	Carcinoma, Hepatocellular	G R C L	View
43	27727182	C2002T	C	C	Carcinoma, Hepatocellular	G R C L	View
44	27727182	G1896A	PreC	C	Carcinoma, Hepatocellular	G R C L	View
45	27727182	T1753V	X	X	Carcinoma, Hepatocellular	G R C L	View
46	27727182	T1938C	C	C	Carcinoma, Hepatocellular	G R C L	View
47	27727182	T2045A	C	C	Carcinoma, Hepatocellular	G R C L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.