All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Carcinoma, Hepatocellular-28373061

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	28373061	A1762T	Core Promoter		Carcinoma, Hepatocellular	G S C L	View
2	28373061	G1764A	Core Promoter		Carcinoma, Hepatocellular	G S C L	View
3	28373061	G1896A	PreC	C	Carcinoma, Hepatocellular	G S C L	View
4	28373061	C1766T			Carcinoma, Hepatocellular	S C L	View
5	28373061	T1753C			Carcinoma, Hepatocellular	S C L	View
6	28373061	E180G	C	C	Carcinoma, Hepatocellular	S C L	View
7	28373061	Q182K	C	C	Carcinoma, Hepatocellular	S C L	View
8	28373061	S181P	C	C	Carcinoma, Hepatocellular	S C L	View
9	28373061	S155P	C	C	Liver Cirrhosis Carcinoma, Hepatocellular	S C L	View
10	28373061	D99G	S	S	Liver Cirrhosis Carcinoma, Hepatocellular	S C L	View
11	28373061	G145R	S	S	Liver Cirrhosis Carcinoma, Hepatocellular	S C L	View
12	28373061	I126S	S	S	Liver Cirrhosis Carcinoma, Hepatocellular	S C L	View
13	28373061	P120T	S	S	Liver Cirrhosis Carcinoma, Hepatocellular	S C L	View
14	28373061	R160G	S	S	Liver Cirrhosis Carcinoma, Hepatocellular	S C L	View
15	28373061	A1896G			Liver Cirrhosis Carcinoma, Hepatocellular	S C L	View
16	28373061	T1762A			Liver Cirrhosis Carcinoma, Hepatocellular	S C L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.