All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
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C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
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PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Carcinoma, Hepatocellular-30406036
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 30406036 P5H
PreC
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
2 30406036 N67A
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
3 30406036 N67S
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
4 30406036 W28X
PreC
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
5 30406036 A80V
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
6 30406036 V91S
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
7 30406036 V91T
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
8 30406036 A80I
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
9 30406036 A80T
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
10 30406036 E180A
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
11 30406036 E64D
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
12 30406036 E77Q
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
13 30406036 F24Y
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
14 30406036 G29D
PreC
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
15 30406036 L116I
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
16 30406036 E77D
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
17 30406036 A131P
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
18 30406036 A34T
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
19 30406036 E113Q
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
20 30406036 E40D
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
21 30406036 I27V
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
22 30406036 M66I
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
23 30406036 P130A
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
24 30406036 P130Q
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
25 30406036 Q177K
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
26 30406036 R179P
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
27 30406036 S12T
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
28 30406036 S155T
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
29 30406036 S21A
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
30 30406036 S35A
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
31 30406036 T147A
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
32 30406036 V149I
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
33 30406036 Y38F
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
34 30406036 A69S
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
35 30406036 E180G
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
36 30406036 E83D
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
37 30406036 I97F
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
38 30406036 M93V
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
39 30406036 N67T
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
40 30406036 S181P
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
41 30406036 S74G
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
42 30406036 S87G
C
C
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
S
C
L
 View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.