All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: Cell line-32730807
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 32730807 A348T
S
S
Cell line
L
View
2 32730807 A435S
S
S
Cell line
I
L
View
3 32730807 A475V
S
S
Cell line
I
L
View
4 32730807 A520S
S
S
Cell line
L
View
5 32730807 A522S
S
S
Cell line
L
View
6 32730807 A522V
S
S
Cell line
L
View
7 32730807 A831V
S
S
Cell line
I
L
View
8 32730807 A845S
S
S
Cell line
L
View
9 32730807 A879S
S
S
Cell line
L
View
10 32730807 D364Y
S
S
Cell line
L
View
11 32730807 D405V
S
S
Cell line
L
View
12 32730807 D467V
S
S
Cell line
L
View
13 32730807 D614G
S
S
Cell line
L
View
14 32730807 D839E
S
S
Cell line
L
View
15 32730807 D839Y
S
S
Cell line
L
View
16 32730807 D936Y
S
S
Cell line
L
View
17 32730807 F338L
S
S
Cell line
L
View
18 32730807 F490L
S
S
Cell line
I
L
View
19 32730807 G1124V
S
S
Cell line
L
View
20 32730807 G446V
S
S
Cell line
L
View
21 32730807 G476S
S
S
Cell line
L
View
22 32730807 H49Y
S
S
Cell line
L
View
23 32730807 H519P
S
S
Cell line
I
L
View
24 32730807 H519Q
S
S
Cell line
L
View
25 32730807 I434K
S
S
Cell line
L
View
26 32730807 I468F
S
S
Cell line
L
View
27 32730807 I468T
S
S
Cell line
L
View
28 32730807 I472V
S
S
Cell line
I
L
View
29 32730807 K378R
S
S
Cell line
L
View
30 32730807 K458N
S
S
Cell line
L
View
31 32730807 K458R
S
S
Cell line
L
View
32 32730807 L452R
S
S
Cell line
I
L
View
33 32730807 L5F
S
S
Cell line
L
View
34 32730807 M1229I
S
S
Cell line
L
View
35 32730807 M1237I
S
S
Cell line
L
View
36 32730807 N1074Q
S
S
Cell line
L
View
37 32730807 N1098Q
S
S
Cell line
L
View
38 32730807 N1134Q
S
S
Cell line
L
View
39 32730807 N1158Q
S
S
Cell line
L
View
40 32730807 N1173Q
S
S
Cell line
L
View
41 32730807 N1194Q
S
S
Cell line
L
View
42 32730807 N122Q
S
S
Cell line
L
View
43 32730807 N149H
S
S
Cell line
L
View
44 32730807 N149Q
S
S
Cell line
L
View
45 32730807 N165Q
S
S
Cell line
L
View
46 32730807 N17Q
S
S
Cell line
L
View
47 32730807 N234Q
S
S
Cell line
I
L
View
48 32730807 N282Q
S
S
Cell line
L
View
49 32730807 N331Q
S
S
Cell line
L
View
50 32730807 N343Q
S
S
Cell line
L
View
51 32730807 N354D
S
S
Cell line
L
View
52 32730807 N354K
S
S
Cell line
L
View
53 32730807 N439K
S
S
Cell line
I
L
View
54 32730807 N603Q
S
S
Cell line
L
View
55 32730807 N616Q
S
S
Cell line
L
View
56 32730807 N61Q
S
S
Cell line
L
View
57 32730807 N657Q
S
S
Cell line
L
View
58 32730807 N709Q
S
S
Cell line
L
View
59 32730807 N717Q
S
S
Cell line
L
View
60 32730807 N74K
S
S
Cell line
L
View
61 32730807 N74Q
S
S
Cell line
L
View
62 32730807 N801Q
S
S
Cell line
L
View
63 32730807 P1263L
S
S
Cell line
L
View
64 32730807 P2C
S
S
Cell line
L
View
65 32730807 P384L
S
S
Cell line
L
View
66 32730807 P491R
S
S
Cell line
L
View
67 32730807 P521S
S
S
Cell line
L
View
68 32730807 Q239K
S
S
Cell line
L
View
69 32730807 Q321L
S
S
Cell line
L
View
70 32730807 Q409E
S
S
Cell line
L
View
71 32730807 Q414E
S
S
Cell line
L
View
72 32730807 Q414P
S
S
Cell line
L
View
73 32730807 Q675H
S
S
Cell line
L
View
74 32730807 R408I
S
S
Cell line
L
View
75 32730807 R509K
S
S
Cell line
L
View
76 32730807 S359N
S
S
Cell line
L
View
77 32730807 S438F
S
S
Cell line
L
View
78 32730807 S939F
S
S
Cell line
L
View
79 32730807 S943R
S
S
Cell line
L
View
80 32730807 S943T
S
S
Cell line
L
View
81 32730807 T478I
S
S
Cell line
L
View
82 32730807 T719A
S
S
Cell line
L
View
83 32730807 V341I
S
S
Cell line
L
View
84 32730807 V367F
S
S
Cell line
L
View
85 32730807 V483A
S
S
Cell line
I
L
View
86 32730807 V483I
S
S
Cell line
L
View
87 32730807 V503F
S
S
Cell line
L
View
88 32730807 V510L
S
S
Cell line
L
View
89 32730807 V615L
S
S
Cell line
L
View
90 32730807 145delY
S
S
Cell line
L
View
91 32730807 Y508H
S
S
Cell line
I
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.