All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: Cell line-37041132
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37041132 A372S
S
S
Cell line
R
S
T
 View
2 37041132 A372T
S
S
Cell line
R
S
T
 View
3 37041132 D614G
S
S
Cell line
R
S
T
 View
4 37041132 E484K
S
S
Cell line
R
S
T
 View
5 37041132 F374K
S
S
Cell line
R
S
T
 View
6 37041132 G413N
S
S
Cell line
R
S
T
 View
7 37041132 G502D
S
S
Cell line
R
S
T
 View
8 37041132 K386E
S
S
Cell line
R
S
T
 View
9 37041132 K386N
S
S
Cell line
R
S
T
 View
10 37041132 K386V
S
S
Cell line
R
S
T
 View
11 37041132 K417N
S
S
Cell line
R
S
T
 View
12 37041132 K417T
S
S
Cell line
R
S
T
 View
13 37041132 L390E
S
S
Cell line
R
S
T
 View
14 37041132 L390S
S
S
Cell line
R
S
T
 View
15 37041132 L390T
S
S
Cell line
R
S
T
 View
16 37041132 L452R
S
S
Cell line
R
S
T
 View
17 37041132 M900V
S
S
Cell line
R
S
T
 View
18 37041132 N440F
S
S
Cell line
R
S
T
 View
19 37041132 N440K
S
S
Cell line
R
S
T
 View
20 37041132 N501F
S
S
Cell line
D
R
S
T
 View
21 37041132 N501T
S
S
Cell line
D
R
S
T
 View
22 37041132 N501Y
S
S
Cell line
R
S
T
 View
23 37041132 P384D
S
S
Cell line
R
S
T
 View
24 37041132 Q493A
S
S
Cell line
D
R
S
T
 View
25 37041132 Q493M
S
S
Cell line
D
R
S
T
 View
26 37041132 Q498H
S
S
Cell line
D
R
S
T
 View
27 37041132 Q498W
S
S
Cell line
R
S
T
 View
28 37041132 Q498Y
S
S
Cell line
D
R
S
T
 View
29 37041132 S205F
S
S
Cell line
D
R
S
T
 View
30 37041132 S383N
S
S
Cell line
R
S
T
 View
31 37041132 S477N
S
S
Cell line
R
S
T
 View
32 37041132 T1117M
S
S
Cell line
R
S
T
 View
33 37041132 T430Q
S
S
Cell line
R
S
T
 View
34 37041132 V382E
S
S
Cell line
R
S
T
 View
35 37041132 Y369N
S
S
Cell line
R
S
T
 View
36 37041132 Y453F
S
S
Cell line
D
R
S
T
 View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.