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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease Cell lineAll COVID-19 Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	37637734	H163W	M	M	Cell line	D	View
2	37637734	H41M	M	M	Cell line		View
3	37637734	H41T	M	M	Cell line		View
4	37637734	H41Y	M	M	Cell line		View
5	37637734	E166A	M	M	Cell line	D	View
6	37637734	L167F	M	M	Cell line	D	View
7	37637734	E166H	M	M	Cell line	D	View
8	37637734	E166I	M	M	Cell line	D	View
9	37637734	E166K	M	M	Cell line	D	View
10	37637734	E166L	M	M	Cell line	D	View
11	37637734	E166Y	M	M	Cell line	D	View
12	37637734	E166Q	M	M	Cell line		View
13	37637734	H275Y	M	M	Cell line	D	View
14	37637734	S31N	M	M	Cell line	D	View
15	37637734	S144K	M	M	Cell line	D	View
16	37637734	S144P	M	M	Cell line	D	View
17	37637734	S144R	M	M	Cell line	D	View
18	37637734	H164N	M	M	Cell line		View
19	37637734	49delM	M	M	Cell line		View
20	37637734	Q189E	M	M	Cell line		View
21	37637734	M165A	M	M	Cell line		View
22	37637734	M165C	M	M	Cell line		View
23	37637734	M165I	M	M	Cell line		View
24	37637734	M165L	M	M	Cell line		View
25	37637734	M165V	M	M	Cell line		View
26	37637734	G15S	M	M	Cell line		View
27	37637734	K90R	M	M	Cell line		View
28	37637734	L205V	M	M	Cell line		View
29	37637734	L89F	M	M	Cell line		View
30	37637734	P108S	M	M	Cell line		View
31	37637734	P132H	M	M	Cell line		View
32	37637734	T21I	M	M	Cell line		View
33	37637734	S144L	M	M	Cell line		View
34	37637734	L50F	M	M	Cell line	D	View
35	37637734	S144D	M	M	Cell line	D	View
36	37637734	S144E	M	M	Cell line	D	View
37	37637734	S144H	M	M	Cell line	D	View
38	37637734	S144Q	M	M	Cell line	D	View
39	37637734	S144T	M	M	Cell line	D	View
40	37637734	S144V	M	M	Cell line	D	View
41	37637734	S144W	M	M	Cell line	D	View
42	37637734	H165Y	M	M	Cell line		View
43	37637734	T135I	M	M	Cell line		View
44	37637734	H172A	M	M	Cell line	D	View
45	37637734	H172Y	M	M	Cell line	D	View
46	37637734	M165Y	M	M	Cell line	D	View
47	37637734	M49I	M	M	Cell line		View
48	37637734	M49L	M	M	Cell line		View
49	37637734	M49T	M	M	Cell line		View
50	37637734	M49V	M	M	Cell line		View
51	37637734	H172C	M	M	Cell line		View
52	37637734	H172D	M	M	Cell line		View
53	37637734	H172E	M	M	Cell line		View
54	37637734	H172G	M	M	Cell line		View
55	37637734	H172I	M	M	Cell line		View
56	37637734	H172K	M	M	Cell line		View
57	37637734	H172L	M	M	Cell line		View
58	37637734	H172M	M	M	Cell line		View
59	37637734	H172N	M	M	Cell line		View
60	37637734	H172R	M	M	Cell line		View
61	37637734	H172S	M	M	Cell line		View
62	37637734	H172T	M	M	Cell line		View
63	37637734	H172V	M	M	Cell line		View
64	37637734	M165D	M	M	Cell line		View
65	37637734	M165F	M	M	Cell line		View
66	37637734	M165G	M	M	Cell line		View
67	37637734	M165H	M	M	Cell line		View
68	37637734	M165K	M	M	Cell line		View
69	37637734	M165P	M	M	Cell line		View
70	37637734	M165R	M	M	Cell line		View
71	37637734	M165W	M	M	Cell line		View
72	37637734	E166G	M	M	Cell line	D	View
73	37637734	E166V	M	M	Cell line	D	View
74	37637734	H172F	M	M	Cell line	D	View
75	37637734	H172Q	M	M	Cell line	D	View
76	37637734	M165T	M	M	Cell line	D	View
77	37637734	Q192A	M	M	Cell line	D	View
78	37637734	Q192C	M	M	Cell line	D	View
79	37637734	Q192F	M	M	Cell line	D	View
80	37637734	Q192H	M	M	Cell line	D	View
81	37637734	Q192I	M	M	Cell line	D	View
82	37637734	Q192L	M	M	Cell line	D	View
83	37637734	Q192P	M	M	Cell line	D	View
84	37637734	Q192S	M	M	Cell line	D	View
85	37637734	Q192T	M	M	Cell line	D	View
86	37637734	Q192V	M	M	Cell line	D	View
87	37637734	Q192W	M	M	Cell line	D	View
88	37637734	S144A	M	M	Cell line	D	View
89	37637734	S144F	M	M	Cell line	D	View
90	37637734	S144G	M	M	Cell line	D	View
91	37637734	S144M	M	M	Cell line	D	View
92	37637734	S144Y	M	M	Cell line	D	View
93	37637734	166delE	M	M	Cell line	D	View
94	37637734	164delH	M	M	Cell line	D	View
95	37637734	172delH	M	M	Cell line	D	View
96	37637734	165delM	M	M	Cell line	D	View
97	37637734	142delN	M	M	Cell line	D	View
98	37637734	189delQ	M	M	Cell line	D	View
99	37637734	192delQ	M	M	Cell line	D	View
100	37637734	144delS	M	M	Cell line	D	View
101	37637734	135delT	M	M	Cell line	D	View