All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: Cell line-38112266
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 38112266 I1210T
S
S
Cell line
G
View
2 38112266 T883I
S
S
Cell line
G
View
3 38112266 D796Y
S
S
Cell line
G
View
4 38112266 A623S
S
S
Cell line
G
View
5 38112266 A626S
S
S
Cell line
G
View
6 38112266 A647S
S
S
Cell line
G
View
7 38112266 A653V
S
S
Cell line
G
View
8 38112266 A684V
S
S
Cell line
G
View
9 38112266 A688V
S
S
Cell line
G
View
10 38112266 A701V
S
S
Cell line
G
View
11 38112266 D614G
S
S
Cell line
G
View
12 38112266 H655Y
S
S
Cell line
G
View
13 38112266 L981F
S
S
Cell line
G
View
14 38112266 N679K
S
S
Cell line
G
View
15 38112266 N764K
S
S
Cell line
G
View
16 38112266 N856K
S
S
Cell line
G
View
17 38112266 N969K
S
S
Cell line
G
View
18 38112266 P681H
S
S
Cell line
G
View
19 38112266 P681R
S
S
Cell line
G
View
20 38112266 Q613H
S
S
Cell line
G
View
21 38112266 Q675H
S
S
Cell line
G
View
22 38112266 Q677H
S
S
Cell line
G
View
23 38112266 Q954H
S
S
Cell line
G
View
24 38112266 S640F
S
S
Cell line
G
View
25 38112266 S680F
S
S
Cell line
G
View
26 38112266 S704L
S
S
Cell line
G
View
27 38112266 T307I
S
S
Cell line
G
View
28 38112266 T678I
S
S
Cell line
G
View
29 38112266 V308L
S
S
Cell line
G
View
30 38112266 V622F
S
S
Cell line
G
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.