All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: Cell line-38224840
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 38224840 V83A
S
S
Cell line
G
R
S
View
2 38224840 T95I
S
S
Cell line
G
R
S
View
3 38224840 144del
S
S
Cell line
G
R
S
View
4 38224840 H146Q
S
S
Cell line
G
R
S
View
5 38224840 Q183E
S
S
Cell line
G
R
S
View
6 38224840 V213E
S
S
Cell line
G
R
S
View
7 38224840 G252V
S
S
Cell line
G
R
S
View
8 38224840 G339H
S
S
Cell line
G
R
S
View
9 38224840 L368I
S
S
Cell line
G
R
S
View
10 38224840 S376A
S
S
Cell line
G
R
S
View
11 38224840 V445P
S
S
Cell line
G
R
S
View
12 38224840 G446S
S
S
Cell line
G
R
S
View
13 38224840 F486S
S
S
Cell line
G
R
S
View
14 38224840 F490S
S
S
Cell line
G
R
S
View
15 38224840 T19I
S
S
Cell line
G
R
S
View
16 38224840 L24S
S
S
Cell line
G
R
S
View
17 38224840 G142D
S
S
Cell line
G
R
S
View
18 38224840 R346T
S
S
Cell line
G
R
S
View
19 38224840 S371F
S
S
Cell line
G
R
S
View
20 38224840 S373P
S
S
Cell line
G
R
S
View
21 38224840 S375F
S
S
Cell line
G
R
S
View
22 38224840 D405N
S
S
Cell line
G
R
S
View
23 38224840 R408S
S
S
Cell line
G
R
S
View
24 38224840 K417N
S
S
Cell line
G
R
S
View
25 38224840 N440K
S
S
Cell line
G
R
S
View
26 38224840 N460K
S
S
Cell line
G
R
S
View
27 38224840 S477N
S
S
Cell line
G
R
S
View
28 38224840 T478K
S
S
Cell line
G
R
S
View
29 38224840 E484A
S
S
Cell line
G
R
S
View
30 38224840 Q498R
S
S
Cell line
G
R
S
View
31 38224840 N501Y
S
S
Cell line
G
R
S
View
32 38224840 Y505H
S
S
Cell line
G
R
S
View
33 38224840 D614G
S
S
Cell line
G
R
S
View
34 38224840 H655Y
S
S
Cell line
G
R
S
View
35 38224840 N679K
S
S
Cell line
G
R
S
View
36 38224840 P681H
S
S
Cell line
G
R
S
View
37 38224840 N764K
S
S
Cell line
G
R
S
View
38 38224840 D796Y
S
S
Cell line
G
R
S
View
39 38224840 Q954H
S
S
Cell line
G
R
S
View
40 38224840 N969K
S
S
Cell line
G
R
S
View
41 38224840 25_27del
S
S
Cell line
G
R
S
View
42 38224840 69_70del
S
S
Cell line
G
R
S
View
43 38224840 V213G
S
S
Cell line
G
R
S
View
44 38224840 G339D
S
S
Cell line
G
R
S
View
45 38224840 T376A
S
S
Cell line
G
R
S
View
46 38224840 K444T
S
S
Cell line
G
R
S
View
47 38224840 L452R
S
S
Cell line
G
R
S
View
48 38224840 F486V
S
S
Cell line
G
R
S
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.