All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: Cell line-39047088
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39047088 I87V
NSP14
ORF1b
Cell line
R
S
View
2 39047088 T21I
M
M
Cell line
D
R
S
View
3 39047088 L50F
M
M
Cell line
D
R
S
View
4 39047088 P108S
M
M
Cell line
D
R
S
View
5 39047088 T135I
M
M
Cell line
D
R
S
View
6 39047088 F140L
M
M
Cell line
D
R
S
View
7 39047088 S144A
M
M
Cell line
D
R
S
View
8 39047088 C160F
M
M
Cell line
D
R
S
View
9 39047088 E166A
M
M
Cell line
D
R
S
View
10 39047088 E166V
M
M
Cell line
D
R
S
View
11 39047088 L167F
M
M
Cell line
D
R
S
View
12 39047088 T169I
M
M
Cell line
D
R
S
View
13 39047088 H172Y
M
M
Cell line
D
R
S
View
14 39047088 A173V
M
M
Cell line
D
R
S
View
15 39047088 V186A
M
M
Cell line
D
R
S
View
16 39047088 R188G
M
M
Cell line
D
R
S
View
17 39047088 A191V
M
M
Cell line
D
R
S
View
18 39047088 A193P
M
M
Cell line
D
R
S
View
19 39047088 P252L
M
M
Cell line
D
R
S
View
20 39047088 S301P
M
M
Cell line
D
R
S
View
21 39047088 T304I
M
M
Cell line
D
R
S
View
22 39047088 I37V
ORF3a
ORF3a
Cell line
R
S
View
23 39047088 S468L
NSP13
ORF1b
Cell line
R
S
View
24 39047088 K94N
NSP13
ORF1b
Cell line
R
S
View
25 39047088 N1543K
NSP13
ORF1b
Cell line
R
S
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.