All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: Cell line-39048693
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39048693 H66R
S
S
Cell line
R
L
View
2 39048693 T95I
S
S
Cell line
R
L
View
3 39048693 I100T
S
S
Cell line
R
L
View
4 39048693 W152L
S
S
Cell line
R
L
View
5 39048693 D215G
S
S
Cell line
R
L
View
6 39048693 H245R
S
S
Cell line
R
L
View
7 39048693 S255F
S
S
Cell line
R
L
View
8 39048693 K309E
S
S
Cell line
R
L
View
9 39048693 E484D
S
S
Cell line
R
L
View
10 39048693 R682W
S
S
Cell line
R
L
View
11 39048693 S813L
S
S
Cell line
R
L
View
12 39048693 L938F
S
S
Cell line
R
L
View
13 39048693 S982L
S
S
Cell line
R
L
View
14 39048693 A1070E
S
S
Cell line
R
L
View
15 39048693 P1162L
S
S
Cell line
R
L
View
16 39048693 E1258V
S
S
Cell line
R
L
View
17 39048693 A21759G
S
S
Cell line
R
L
View
18 39048693 C21846T
S
S
Cell line
R
L
View
19 39048693 T21861C
S
S
Cell line
R
L
View
20 39048693 G22017T
S
S
Cell line
R
L
View
21 39048693 A22206G
S
S
Cell line
R
L
View
22 39048693 A22296G
S
S
Cell line
R
L
View
23 39048693 C22326T
S
S
Cell line
R
L
View
24 39048693 A22487G
S
S
Cell line
R
L
View
25 39048693 A23014T
S
S
Cell line
R
L
View
26 39048693 C23606T
S
S
Cell line
R
L
View
27 39048693 A23999C
S
S
Cell line
R
L
View
28 39048693 G24000T
S
S
Cell line
R
L
View
29 39048693 C24374T
S
S
Cell line
R
L
View
30 39048693 C24507T
S
S
Cell line
R
L
View
31 39048693 C24771A
S
S
Cell line
R
L
View
32 39048693 C25047T
S
S
Cell line
R
L
View
33 39048693 A25335T
S
S
Cell line
R
L
View
34 39048693 S67F
ORF8
ORF8
Cell line
R
L
View
35 39048693 C28093T
ORF8
ORF8
Cell line
R
L
View
36 39048693 T9I
ORF3a
ORF3a
Cell line
R
L
View
37 39048693 C25418T
ORF3a
ORF3a
Cell line
R
L
View
38 39048693 T35I
NSP9
ORF1a
Cell line
R
L
View
39 39048693 C12789T
NSP9
ORF1a
Cell line
R
L
View
40 39048693 L56F
NSP7
ORF1a
Cell line
R
L
View
41 39048693 C12008T
NSP7
ORF1a
Cell line
R
L
View
42 39048693 T21I
NSP5
ORF1a
Cell line
R
L
View
43 39048693 C10116T
NSP5
ORF1a
Cell line
R
L
View
44 39048693 I541V
NSP3
ORF1a
Cell line
R
L
View
45 39048693 S1087F
NSP3
ORF1a
Cell line
R
L
View
46 39048693 I1489T
NSP3
ORF1a
Cell line
R
L
View
47 39048693 S1717L
NSP3
ORF1a
Cell line
R
L
View
48 39048693 H1841Y
NSP3
ORF1a
Cell line
R
L
View
49 39048693 A4340G
NSP3
ORF1a
Cell line
R
L
View
50 39048693 C5979T
NSP3
ORF1a
Cell line
R
L
View
51 39048693 T7185C
NSP3
ORF1a
Cell line
R
L
View
52 39048693 C7869T
NSP3
ORF1a
Cell line
R
L
View
53 39048693 C8240T
NSP3
ORF1a
Cell line
R
L
View
54 39048693 F529L
NSP2
ORF1a
Cell line
R
L
View
55 39048693 T2392A
NSP2
ORF1a
Cell line
R
L
View
56 39048693 E21A
NSP15
ORF1b
Cell line
R
L
View
57 39048693 A19682C
NSP15
ORF1b
Cell line
R
L
View
58 39048693 R212S
NSP14
ORF1b
Cell line
R
L
View
59 39048693 E453D
NSP14
ORF1b
Cell line
R
L
View
60 39048693 T524I
NSP14
ORF1b
Cell line
R
L
View
61 39048693 A18675C
NSP14
ORF1b
Cell line
R
L
View
62 39048693 G19398T
NSP14
ORF1b
Cell line
R
L
View
63 39048693 C19610T
NSP14
ORF1b
Cell line
R
L
View
64 39048693 T393I
N
N
Cell line
R
L
View
65 39048693 C29451T
N
N
Cell line
R
L
View
66 39048693 V5L
E
E
Cell line
R
L
View
67 39048693 V5F
E
E
Cell line
R
L
View
68 39048693 F26L
E
E
Cell line
R
L
View
69 39048693 G26257C
E
E
Cell line
R
L
View
70 39048693 G26257T
E
E
Cell line
R
L
View
71 39048693 T26320C
E
E
Cell line
R
L
View
72 39048693 D614G
S
S
Cell line
R
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.