All Curated Mutation Sites in HCV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HCV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

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Keyword: HCV Infection-25140696

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	25140696	C316Y	NS5B	NS5B	HCV Infection	D G R S C	View
2	25140696	C445F	NS5B	NS5B	HCV Infection	D G R S C	View
3	25140696	C445Y	NS5B	NS5B	HCV Infection	D G R S C	View
4	25140696	I482L	NS5B	NS5B	HCV Infection	D G R S C	View
5	25140696	I482T	NS5B	NS5B	HCV Infection	D G R S C	View
6	25140696	M414L	NS5B	NS5B	HCV Infection	D G R S C	View
7	25140696	M414V	NS5B	NS5B	HCV Infection	D G R S C	View
8	25140696	M423I	NS5B	NS5B	HCV Infection	D G R S C	View
9	25140696	M423T	NS5B	NS5B	HCV Infection	D G R S C	View
10	25140696	M423V	NS5B	NS5B	HCV Infection	D G R S C	View
11	25140696	V321I	NS5B	NS5B	HCV Infection	D G R S C	View
12	25140696	V494A	NS5B	NS5B	HCV Infection	D G R S C	View
13	25140696	V494I	NS5B	NS5B	HCV Infection	D G R S C	View
14	25140696	Y448C	NS5B	NS5B	HCV Infection	D G R S C	View
15	25140696	Y448H	NS5B	NS5B	HCV Infection	D G R S C	View
16	25140696	Y452H	NS5B	NS5B	HCV Infection	D G R S C	View
17	25140696	A156G	NS3	NS3	HCV Infection	D G R S C	View
18	25140696	A156T	NS3	NS3	HCV Infection	D G R S C	View
19	25140696	D168G	NS3	NS3	HCV Infection	D G R S C	View
20	25140696	D168N	NS3	NS3	HCV Infection	D G R S C	View
21	25140696	D168V	NS3	NS3	HCV Infection	D G R S C	View
22	25140696	I170T	NS3	NS3	HCV Infection	D G R S C	View
23	25140696	Q80K	NS3	NS3	HCV Infection	D G R S C	View
24	25140696	Q80R	NS3	NS3	HCV Infection	D G R S C	View
25	25140696	R155K	NS3	NS3	HCV Infection	D G R S C	View
26	25140696	V158I	NS3	NS3	HCV Infection	D G R S C	View
27	25140696	V36A	NS3	NS3	HCV Infection	D G R S C	View
28	25140696	V36M	NS3	NS3	HCV Infection	D G R S C	View
29	25140696	V55A	NS3	NS3	HCV Infection	D G R S C	View
30	25140696	V55I	NS3	NS3	HCV Infection	D G R S C	View
31	25140696	Q41H			HCV Infection	G R S C	View
32	25140696	S138P			HCV Infection	G R S C	View
33	25140696	V158A			HCV Infection	G R S C	View
34	25140696	V158G			HCV Infection	G R S C	View
35	25140696	V158M			HCV Infection	G R S C	View
36	25140696	V170M			HCV Infection	G R S C	View
37	25140696	A421V	NS5B	NS5B	HCV Infection	D G R S C	View
38	25140696	L320F	NS5B	NS5B	HCV Infection	D G R S C	View
39	25140696	L320I	NS5B	NS5B	HCV Infection	D G R S C	View
40	25140696	L392I	NS5B	NS5B	HCV Infection	D G R S C	View
41	25140696	M426T	NS5B	NS5B	HCV Infection	D G R S C	View
42	25140696	D168E	NS3	NS3	HCV Infection	D G R S C	View
43	25140696	T54S	NS3	NS3	HCV Infection	D G R S C	View
44	25140696	F43L			HCV Infection	G R S C	View
45	25140696	C316N	NS5B	NS5B	HCV Infection	D G R S C	View
46	25140696	M414I	NS5B	NS5B	HCV Infection	D G R S C	View
47	25140696	M414T	NS5B	NS5B	HCV Infection	D G R S C	View
48	25140696	P496A	NS5B	NS5B	HCV Infection	D G R S C	View
49	25140696	P496S	NS5B	NS5B	HCV Infection	D G R S C	View
50	25140696	M175L	NS3	NS3	HCV Infection	D G R S C	View
51	25140696	V170A	NS3	NS3	HCV Infection	D G R S C	View
52	25140696	V170T	NS3	NS3	HCV Infection	D G R S C	View
53	25140696	Q80L			HCV Infection	G R S C	View
54	25140696	V55N			HCV Infection	G R S C	View
55	25140696	S282T	NS5B	NS5B	HCV Infection	D R S C	View

Contents
Description

The table shows all curated mutation sites of HCV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.