All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B, Chronic-20382061
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 20382061 C137G
S
S
Hepatitis B, Chronic
G
I
C
L
View
2 20382061 D144E
S
S
Hepatitis B, Chronic
G
I
C
L
View
3 20382061 G130R
S
S
Hepatitis B, Chronic
G
I
C
L
View
4 20382061 G145R
S
S
Hepatitis B, Chronic
G
I
C
L
View
5 20382061 I110V
S
S
Hepatitis B, Chronic
G
I
C
L
View
6 20382061 L109I
S
S
Hepatitis B, Chronic
G
I
C
L
View
7 20382061 P120T
S
S
Hepatitis B, Chronic
G
I
C
L
View
8 20382061 P127T
S
S
Hepatitis B, Chronic
G
I
C
L
View
9 20382061 S132A
S
S
Hepatitis B, Chronic
G
I
C
L
View
10 20382061 Y100C
S
S
Hepatitis B, Chronic
G
I
C
L
View
11 20382061 Y134N
S
S
Hepatitis B, Chronic
G
I
C
L
View
12 20382061 S117I
S
S
Hepatitis B, Chronic
G
I
C
L
View
13 20382061 C137L
S
S
Hepatitis B, Chronic
G
I
C
L
View
14 20382061 M133I
S
S
Hepatitis B, Chronic
G
I
C
L
View
15 20382061 S143L
S
S
Hepatitis B, Chronic
G
I
C
L
View
16 20382061 A181V
RT
P
Hepatitis B, Chronic
D
G
C
L
View
17 20382061 A194T
RT
P
Hepatitis B, Chronic
D
G
C
L
View
18 20382061 I233V
RT
P
Hepatitis B, Chronic
D
G
C
L
View
19 20382061 L180M
RT
P
Hepatitis B, Chronic
D
G
C
L
View
20 20382061 M204I
RT
P
Hepatitis B, Chronic
D
G
C
L
View
21 20382061 Q215S
RT
P
Hepatitis B, Chronic
D
G
C
L
View
22 20382061 A194V
RT
P
Hepatitis B, Chronic
D
G
C
L
View
23 20382061 M204V
RT
P
Hepatitis B, Chronic
D
G
C
L
View
24 20382061 N236T
RT
P
Hepatitis B, Chronic
D
G
C
L
View
25 20382061 S202C
RT
P
Hepatitis B, Chronic
D
G
C
L
View
26 20382061 A181T
RT
P
Hepatitis B, Chronic
D
G
C
L
View
27 20382061 A194G
RT
P
Hepatitis B, Chronic
D
G
C
L
View
28 20382061 I233S
RT
P
Hepatitis B, Chronic
D
G
C
L
View
29 20382061 L180V
RT
P
Hepatitis B, Chronic
G
C
L
View
30 20382061 L80F
RT
P
Hepatitis B, Chronic
D
G
C
L
View
31 20382061 M250R
RT
P
Hepatitis B, Chronic
G
C
L
View
32 20382061 N236S
RT
P
Hepatitis B, Chronic
D
G
C
L
View
33 20382061 Q215H
RT
P
Hepatitis B, Chronic
G
C
L
View
34 20382061 Q215P
RT
P
Hepatitis B, Chronic
D
G
C
L
View
35 20382061 V214P
RT
P
Hepatitis B, Chronic
D
G
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.