All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B, Chronic-24630522

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	24630522	L216X	RT	P	Hepatitis B, Chronic	G R L	View
2	24630522	L95X	RT	P	Hepatitis B, Chronic	G R L	View
3	24630522	V173L	RT	P	Hepatitis B, Chronic	D G R L	View
4	24630522	L180M	RT	P	Hepatitis B, Chronic	D G R L	View
5	24630522	L80I	RT	P	Hepatitis B, Chronic	D G R L	View
6	24630522	L80V	RT	P	Hepatitis B, Chronic	D G R L	View
7	24630522	M204I	RT	P	Hepatitis B, Chronic	D G R L	View
8	24630522	F221Y	RT	P	Hepatitis B, Chronic	D G R L	View
9	24630522	I266G	RT	P	Hepatitis B, Chronic	G R L	View
10	24630522	L91I	RT	P	Hepatitis B, Chronic	D G R L	View
11	24630522	N238D	RT	P	Hepatitis B, Chronic	D G R L	View
12	24630522	Q215P	RT	P	Hepatitis B, Chronic	D G R L	View
13	24630522	C256S	RT	P	Hepatitis B, Chronic	D G R L	View
14	24630522	T128I	RT	P	Hepatitis B, Chronic	D G R L	View
15	24630522	S207R	S	S	Hepatitis B, Chronic	G R L	View
16	24630522	I91L	RT	P	Hepatitis B, Chronic	G R L	View
17	24630522	P120S	S	S	Hepatitis B, Chronic	G R L	View
18	24630522	A113G	RT	P	Hepatitis B, Chronic	G R L	View
19	24630522	A181T	RT	P	Hepatitis B, Chronic	D G R L	View
20	24630522	A297S	RT	P	Hepatitis B, Chronic	G R L	View
21	24630522	A38E	P	P	Hepatitis B, Chronic	G R L	View
22	24630522	C256G	RT	P	Hepatitis B, Chronic	G R L	View
23	24630522	C332N	RT	P	Hepatitis B, Chronic	G R L	View
24	24630522	D123N	RT	P	Hepatitis B, Chronic	G R L	View
25	24630522	D124Y	RT	P	Hepatitis B, Chronic	G R L	View
26	24630522	D263E	RT	P	Hepatitis B, Chronic	G R L	View
27	24630522	D283N	RT	P	Hepatitis B, Chronic	G R L	View
28	24630522	E271Q	RT	P	Hepatitis B, Chronic	G R L	View
29	24630522	F122I	RT	P	Hepatitis B, Chronic	G R L	View
30	24630522	F151Y	RT	P	Hepatitis B, Chronic	G R L	View
31	24630522	F300S	P	P	Hepatitis B, Chronic	G R L	View
32	24630522	G107R	P	P	Hepatitis B, Chronic	G R L	View
33	24630522	G127E	RT	P	Hepatitis B, Chronic	G R L	View
34	24630522	G127R	RT	P	Hepatitis B, Chronic	G R L	View
35	24630522	G295S	RT	P	Hepatitis B, Chronic	G R L	View
36	24630522	H124Y	RT	P	Hepatitis B, Chronic	G R L	View
37	24630522	H248N	P	P	Hepatitis B, Chronic	G R L	View
38	24630522	H35Y	P	P	Hepatitis B, Chronic	G R L	View
39	24630522	I145P	RT	P	Hepatitis B, Chronic	G R L	View
40	24630522	I266R	RT	P	Hepatitis B, Chronic	G R L	View
41	24630522	I266V	RT	P	Hepatitis B, Chronic	G R L	View
42	24630522	L115S	RT	P	Hepatitis B, Chronic	G R L	View
43	24630522	L145M	RT	P	Hepatitis B, Chronic	G R L	View
44	24630522	L231S	P	P	Hepatitis B, Chronic	G R L	View
45	24630522	L247F	P	P	Hepatitis B, Chronic	G R L	View
46	24630522	L29V	P	P	Hepatitis B, Chronic	G R L	View
47	24630522	L336M	P	P	Hepatitis B, Chronic	G R L	View
48	24630522	L72F	P	P	Hepatitis B, Chronic	G R L	View
49	24630522	L93S	RT	P	Hepatitis B, Chronic	G R L	View
50	24630522	M204V	RT	P	Hepatitis B, Chronic	G R L	View
51	24630522	M309K	P	P	Hepatitis B, Chronic	G R L	View
52	24630522	M309L	RT	P	Hepatitis B, Chronic	G R L	View
53	24630522	N118T	RT	P	Hepatitis B, Chronic	G R L	View
54	24630522	N123D	P	P	Hepatitis B, Chronic	G R L	View
55	24630522	N124H	RT	P	Hepatitis B, Chronic	G R L	View
56	24630522	N131D	P	P	Hepatitis B, Chronic	G R L	View
57	24630522	N139S	RT	P	Hepatitis B, Chronic	G R L	View
58	24630522	N238Q	RT	P	Hepatitis B, Chronic	G R L	View
59	24630522	N279H	RT	P	Hepatitis B, Chronic	G R L	View
60	24630522	N76D	RT	P	Hepatitis B, Chronic	G R L	View
61	24630522	N76P	RT	P	Hepatitis B, Chronic	G R L	View
62	24630522	Q149K	RT	P	Hepatitis B, Chronic	G R L	View
63	24630522	Q149P	P	P	Hepatitis B, Chronic	G R L	View
64	24630522	Q267H	P	P	Hepatitis B, Chronic	G R L	View
65	24630522	Q302R	P	P	Hepatitis B, Chronic	G R L	View
66	24630522	Q334K	RT	P	Hepatitis B, Chronic	G R L	View
67	24630522	R110G	RT	P	Hepatitis B, Chronic	G R L	View
68	24630522	R110K	RT	P	Hepatitis B, Chronic	G R L	View
69	24630522	R274K	P	P	Hepatitis B, Chronic	G R L	View
70	24630522	R55G	RT	P	Hepatitis B, Chronic	G R L	View
71	24630522	S143P	RT	P	Hepatitis B, Chronic	G R L	View
72	24630522	S259N	RT	P	Hepatitis B, Chronic	G R L	View
73	24630522	S259T	RT	P	Hepatitis B, Chronic	G R L	View
74	24630522	S317A	RT	P	Hepatitis B, Chronic	G R L	View
75	24630522	S78A	P	P	Hepatitis B, Chronic	G R L	View
76	24630522	S78T	RT	P	Hepatitis B, Chronic	G R L	View
77	24630522	T222A	RT	P	Hepatitis B, Chronic	G R L	View
78	24630522	T54N	RT	P	Hepatitis B, Chronic	G R L	View
79	24630522	V142E	RT	P	Hepatitis B, Chronic	G R L	View
80	24630522	V253I	RT	P	Hepatitis B, Chronic	G R L	View
81	24630522	V278I	RT	P	Hepatitis B, Chronic	G R L	View
82	24630522	V30G	RT	P	Hepatitis B, Chronic	G R L	View
83	24630522	Y124H	P	P	Hepatitis B, Chronic	G R L	View
84	24630522	Y257C	P	P	Hepatitis B, Chronic	G R L	View
85	24630522	Y257L	RT	P	Hepatitis B, Chronic	G R L	View
86	24630522	Y257W	P	P	Hepatitis B, Chronic	G R L	View
87	24630522	Y335N	RT	P	Hepatitis B, Chronic	G R L	View
88	24630522	Y54F	RT	P	Hepatitis B, Chronic	G R L	View
89	24630522	Y54T	RT	P	Hepatitis B, Chronic	G R L	View
90	24630522	A38T	RT	P	Hepatitis B, Chronic	G R L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.