All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B, Chronic-27006281

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	27006281	L180M	RT	P	Hepatitis B, Chronic	G R L	View
2	27006281	L80V	RT	P	Hepatitis B, Chronic	G R L	View
3	27006281	M204I	RT	P	Hepatitis B, Chronic	G R L	View
4	27006281	M204V	RT	P	Hepatitis B, Chronic	G R L	View
5	27006281	N134D	RT	P	Hepatitis B, Chronic	G R L	View
6	27006281	N134S	RT	P	Hepatitis B, Chronic	G R L	View
7	27006281	T126A	S	S	Hepatitis B, Chronic	G R I L	View
8	27006281	T126S	S	S	Hepatitis B, Chronic	G R I L	View
9	27006281	I169M	RT	P	Hepatitis B, Chronic	G R L	View
10	27006281	M133I	S	S	Hepatitis B, Chronic	G R I L	View
11	27006281	M133L	S	S	Hepatitis B, Chronic	G R I L	View
12	27006281	M133T	S	S	Hepatitis B, Chronic	G R I L	View
13	27006281	G145A	S	S	Hepatitis B, Chronic	G R I L	View
14	27006281	G145R	S	S	Hepatitis B, Chronic	G R I L	View
15	27006281	S256C	RT	P	Hepatitis B, Chronic	G R L	View
16	27006281	S256G	RT	P	Hepatitis B, Chronic	G R L	View
17	27006281	K122R	S	S	Hepatitis B, Chronic	G R I L	View
18	27006281	P127T	S	S	Hepatitis B, Chronic	G R I L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.