All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B, Chronic-27787680
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 27787680 N248H
RT
P
Hepatitis B, Chronic
D
G
R
C
L
View
2 27787680 N238D
RT
P
Hepatitis B, Chronic
D
G
R
C
L
View
3 27787680 N238T
RT
P
Hepatitis B, Chronic
D
G
R
C
L
View
4 27787680 Q215P
RT
P
Hepatitis B, Chronic
D
G
R
C
L
View
5 27787680 T184A
RT
P
Hepatitis B, Chronic
D
G
R
C
L
View
6 27787680 V207L
RT
P
Hepatitis B, Chronic
D
G
R
C
L
View
7 27787680 V207M
RT
P
Hepatitis B, Chronic
D
G
R
C
L
View
8 27787680 A128V
S
S
Hepatitis B, Chronic
G
R
C
L
View
9 27787680 A159P
S
S
Hepatitis B, Chronic
G
R
C
L
View
10 27787680 C107W
S
S
Hepatitis B, Chronic
G
R
C
L
View
11 27787680 C138R
S
S
Hepatitis B, Chronic
G
R
C
L
View
12 27787680 C147Y
S
S
Hepatitis B, Chronic
G
R
C
L
View
13 27787680 C149Y
S
S
Hepatitis B, Chronic
G
R
C
L
View
14 27787680 F134L
S
S
Hepatitis B, Chronic
G
R
C
L
View
15 27787680 F134Y
S
S
Hepatitis B, Chronic
G
R
C
L
View
16 27787680 G130N
S
S
Hepatitis B, Chronic
G
R
C
L
View
17 27787680 L109V
S
S
Hepatitis B, Chronic
G
R
C
L
View
18 27787680 M198I
S
S
Hepatitis B, Chronic
G
R
C
L
View
19 27787680 P127T
S
S
Hepatitis B, Chronic
G
R
C
L
View
20 27787680 Q101R
S
S
Hepatitis B, Chronic
G
R
C
L
View
21 27787680 T118V
S
S
Hepatitis B, Chronic
G
R
C
L
View
22 27787680 T143M
S
S
Hepatitis B, Chronic
G
R
C
L
View
23 27787680 V184A
S
S
Hepatitis B, Chronic
G
R
C
L
View
24 27787680 W182X
S
S
Hepatitis B, Chronic
G
R
C
L
View
25 27787680 T1858C
C
C
Hepatitis B, Chronic
G
R
C
L
View
26 27787680 A1762T
BCP
Hepatitis B, Chronic
G
R
C
L
View
27 27787680 G1764A
BCP
Hepatitis B, Chronic
G
R
C
L
View
28 27787680 G1896A
PreC
C
Hepatitis B, Chronic
G
R
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.