All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B, Chronic-29859062
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 29859062 M204V
RT
P
Hepatitis B, Chronic
D
G
R
S
C
L
View
2 29859062 P120T
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
3 29859062 E164D
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
4 29859062 I195M
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
5 29859062 I196S
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
6 29859062 M204I
RT
P
Hepatitis B, Chronic
D
G
R
S
C
L
View
7 29859062 V173L
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
8 29859062 C138Y
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
9 29859062 C139S
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
10 29859062 D144A
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
11 29859062 D144E
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
12 29859062 G130R
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
13 29859062 G145A
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
14 29859062 G145R
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
15 29859062 P120A
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
16 29859062 P127L
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
17 29859062 P142S
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
18 29859062 T114R
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
19 29859062 T123A
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
20 29859062 T123N
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
21 29859062 T126N
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
22 29859062 T126S
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
23 29859062 T140S
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
24 29859062 Y134L
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
25 29859062 M133I
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
26 29859062 M133L
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
27 29859062 M133T
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
28 29859062 N146S
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
29 29859062 Q101K
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
30 29859062 Q129N
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
31 29859062 Q129R
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
32 29859062 T131I
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
33 29859062 A181T
RT
P
Hepatitis B, Chronic
D
G
R
S
C
L
View
34 29859062 A181V
RT
P
Hepatitis B, Chronic
D
G
R
S
C
L
View
35 29859062 L180M
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
36 29859062 N236T
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
37 29859062 A128V
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
38 29859062 G130N
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
39 29859062 P120S
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.