All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B, Chronic-35293188

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	35293188	D144E	S	S	Hepatitis B, Chronic	G R I	View
2	35293188	E164A	S	S	Hepatitis B, Chronic	G R	View
3	35293188	I226S	S	S	Hepatitis B, Chronic	G R	View
4	35293188	L222I	S	S	Hepatitis B, Chronic	G R	View
5	35293188	L222R	S	S	Hepatitis B, Chronic	G R	View
6	35293188	P11L	S	S	Hepatitis B, Chronic	G R	View
7	35293188	R24K	S	S	Hepatitis B, Chronic	G R	View
8	35293188	S114A	S	S	Hepatitis B, Chronic	G R	View
9	35293188	S114P	S	S	Hepatitis B, Chronic	G R	View
10	35293188	S174N	S	S	Hepatitis B, Chronic	G R	View
11	35293188	S207H	S	S	Hepatitis B, Chronic	G R	View
12	35293188	S207N	S	S	Hepatitis B, Chronic	G R	View
13	35293188	S207R	S	S	Hepatitis B, Chronic	G R	View
14	35293188	T189I	S	S	Hepatitis B, Chronic	G R	View
15	35293188	V118T	S	S	Hepatitis B, Chronic	G R	View
16	35293188	V128A	S	S	Hepatitis B, Chronic	G R	View
17	35293188	V177A	S	S	Hepatitis B, Chronic	G R	View
18	35293188	Y134H	S	S	Hepatitis B, Chronic	G R	View
19	35293188	G145R	S	S	Hepatitis B, Chronic	G R I	View
20	35293188	S143L	S	S	Hepatitis B, Chronic	G R I	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.