All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-12050364
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 12050364 A119F
PreS1
S
Hepatitis B Virus Infection
View
2 12050364 I97L
C
C
Hepatitis B Virus Infection
View
3 12050364 F97L
C
C
Hepatitis B Virus Infection
View
4 12050364 A119I
RT
P
Hepatitis B Virus Infection
View
5 12050364 A119L
PreS
S
Hepatitis B Virus Infection
View
6 12050364 L112F
PreS
S
Hepatitis B Virus Infection
View
7 12050364 L112I
PreS
S
Hepatitis B Virus Infection
View
8 12050364 G299A
RT
P
Hepatitis B Virus Infection
View
9 12050364 G299D
RT
P
Hepatitis B Virus Infection
View
10 12050364 G299V
RT
P
Hepatitis B Virus Infection
View
11 12050364 H288L
RT
P
Hepatitis B Virus Infection
View
12 12050364 K293Q
RT
P
Hepatitis B Virus Infection
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.