All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-12780567
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 12780567 D144A
S
S
Hepatitis B Virus Infection
G
L
View
2 12780567 G145R
S
S
Hepatitis B Virus Infection
G
I
L
View
3 12780567 L180M
RT
P
Hepatitis B Virus Infection
D
L
View
4 12780567 M204I
RT
P
Hepatitis B Virus Infection
D
L
View
5 12780567 M204V
RT
P
Hepatitis B Virus Infection
D
L
View
6 12780567 D144G
S
S
Hepatitis B Virus Infection
G
L
View
7 12780567 T118A
S
S
Hepatitis B Virus Infection
G
L
View
8 12780567 A194V
S
S
Hepatitis B Virus Infection
G
L
View
9 12780567 C256G
P
P
Hepatitis B Virus Infection
G
L
View
10 12780567 D134D
P
P
Hepatitis B Virus Infection
G
L
View
11 12780567 D134V
P
P
Hepatitis B Virus Infection
G
L
View
12 12780567 D144D
S
S
Hepatitis B Virus Infection
G
L
View
13 12780567 E144D
S
S
Hepatitis B Virus Infection
G
L
View
14 12780567 E144G
S
S
Hepatitis B Virus Infection
G
L
View
15 12780567 F212F
S
S
Hepatitis B Virus Infection
G
L
View
16 12780567 F212S
S
S
Hepatitis B Virus Infection
G
L
View
17 12780567 G119G
S
S
Hepatitis B Virus Infection
G
L
View
18 12780567 G119R
S
S
Hepatitis B Virus Infection
G
L
View
19 12780567 G127E
P
P
Hepatitis B Virus Infection
G
L
View
20 12780567 G127G
P
P
Hepatitis B Virus Infection
G
L
View
21 12780567 G145E
S
S
Hepatitis B Virus Infection
G
L
View
22 12780567 G145G
S
S
Hepatitis B Virus Infection
G
L
View
23 12780567 G145K
S
S
Hepatitis B Virus Infection
G
L
View
24 12780567 G266G
P
P
Hepatitis B Virus Infection
G
L
View
25 12780567 G266T
P
P
Hepatitis B Virus Infection
G
L
View
26 12780567 H124D
P
P
Hepatitis B Virus Infection
G
L
View
27 12780567 H124Q
P
P
Hepatitis B Virus Infection
G
L
View
28 12780567 H126R
P
P
Hepatitis B Virus Infection
G
L
View
29 12780567 H271D
P
P
Hepatitis B Virus Infection
G
L
View
30 12780567 H271Q
P
P
Hepatitis B Virus Infection
G
L
View
31 12780567 I110I
S
S
Hepatitis B Virus Infection
G
L
View
32 12780567 I110L
S
S
Hepatitis B Virus Infection
G
L
View
33 12780567 I266G
P
P
Hepatitis B Virus Infection
G
L
View
34 12780567 I266T
P
P
Hepatitis B Virus Infection
G
L
View
35 12780567 L157L
P
P
Hepatitis B Virus Infection
G
L
View
36 12780567 L157M
P
P
Hepatitis B Virus Infection
G
L
View
37 12780567 L164M
P
P
Hepatitis B Virus Infection
G
L
View
38 12780567 M133I
S
S
Hepatitis B Virus Infection
G
L
View
39 12780567 M133M
S
S
Hepatitis B Virus Infection
G
L
View
40 12780567 N118D
P
P
Hepatitis B Virus Infection
G
L
View
41 12780567 N118N
P
P
Hepatitis B Virus Infection
G
L
View
42 12780567 N118T
P
P
Hepatitis B Virus Infection
G
L
View
43 12780567 N124D
P
P
Hepatitis B Virus Infection
G
L
View
44 12780567 N124Q
P
P
Hepatitis B Virus Infection
G
L
View
45 12780567 N238H
P
P
Hepatitis B Virus Infection
G
L
View
46 12780567 N238N
P
P
Hepatitis B Virus Infection
G
L
View
47 12780567 P127S
S
S
Hepatitis B Virus Infection
G
L
View
48 12780567 P127T
S
S
Hepatitis B Virus Infection
G
L
View
49 12780567 P135A
S
S
Hepatitis B Virus Infection
G
L
View
50 12780567 P135P
S
S
Hepatitis B Virus Infection
G
L
View
51 12780567 P203P
S
S
Hepatitis B Virus Infection
G
L
View
52 12780567 P203Q
S
S
Hepatitis B Virus Infection
G
L
View
53 12780567 P203R
S
S
Hepatitis B Virus Infection
G
L
View
54 12780567 P237T
P
P
Hepatitis B Virus Infection
G
L
View
55 12780567 Q149K
P
P
Hepatitis B Virus Infection
G
L
View
56 12780567 Q149Q
P
P
Hepatitis B Virus Infection
G
L
View
57 12780567 Q215P
P
P
Hepatitis B Virus Infection
G
L
View
58 12780567 Q215S
P
P
Hepatitis B Virus Infection
G
L
View
59 12780567 R153Q
P
P
Hepatitis B Virus Infection
G
L
View
60 12780567 R266G
P
P
Hepatitis B Virus Infection
G
L
View
61 12780567 R266T
P
P
Hepatitis B Virus Infection
G
L
View
62 12780567 S135F
P
P
Hepatitis B Virus Infection
G
L
View
63 12780567 S135Y
P
P
Hepatitis B Virus Infection
G
L
View
64 12780567 S143C
P
P
Hepatitis B Virus Infection
G
L
View
65 12780567 S143S
P
P
Hepatitis B Virus Infection
G
L
View
66 12780567 S204R
S
S
Hepatitis B Virus Infection
G
L
View
67 12780567 S207R
S
S
Hepatitis B Virus Infection
G
L
View
68 12780567 S210R
S
S
Hepatitis B Virus Infection
G
L
View
69 12780567 S210S
S
S
Hepatitis B Virus Infection
G
L
View
70 12780567 S213T
P
P
Hepatitis B Virus Infection
G
L
View
71 12780567 S219A
P
P
Hepatitis B Virus Infection
G
L
View
72 12780567 S219S
P
P
Hepatitis B Virus Infection
G
L
View
73 12780567 S256G
P
P
Hepatitis B Virus Infection
G
L
View
74 12780567 T116N
S
S
Hepatitis B Virus Infection
G
L
View
75 12780567 T118T
S
S
Hepatitis B Virus Infection
G
L
View
76 12780567 T126I
S
S
Hepatitis B Virus Infection
G
L
View
77 12780567 T126S
S
S
Hepatitis B Virus Infection
G
L
View
78 12780567 T126T
S
S
Hepatitis B Virus Infection
G
L
View
79 12780567 T127S
S
S
Hepatitis B Virus Infection
G
L
View
80 12780567 T127T
S
S
Hepatitis B Virus Infection
G
L
View
81 12780567 T140I
S
S
Hepatitis B Virus Infection
G
L
View
82 12780567 T140T
S
S
Hepatitis B Virus Infection
G
L
View
83 12780567 T189I
S
S
Hepatitis B Virus Infection
G
L
View
84 12780567 T189T
S
S
Hepatitis B Virus Infection
G
L
View
85 12780567 V142I
P
P
Hepatitis B Virus Infection
G
L
View
86 12780567 V142V
P
P
Hepatitis B Virus Infection
G
L
View
87 12780567 V266G
P
P
Hepatitis B Virus Infection
G
L
View
88 12780567 V266T
P
P
Hepatitis B Virus Infection
G
L
View
89 12780567 W153Q
P
P
Hepatitis B Virus Infection
G
L
View
90 12780567 Y124D
P
P
Hepatitis B Virus Infection
G
L
View
91 12780567 Y124H
P
P
Hepatitis B Virus Infection
G
L
View
92 12780567 Y124Q
P
P
Hepatitis B Virus Infection
G
L
View
93 12780567 Y124Y
P
P
Hepatitis B Virus Infection
G
L
View
94 12780567 Y126C
P
P
Hepatitis B Virus Infection
G
L
View
95 12780567 Y126Y
P
P
Hepatitis B Virus Infection
G
L
View
96 12780567 Y134F
S
S
Hepatitis B Virus Infection
G
L
View
97 12780567 Y134Y
S
S
Hepatitis B Virus Infection
G
L
View
98 12780567 Y135F
P
P
Hepatitis B Virus Infection
G
L
View
99 12780567 Y135Y
P
P
Hepatitis B Virus Infection
G
L
View
100 12780567 Y161F
S
S
Hepatitis B Virus Infection
G
L
View
101 12780567 Y200F
S
S
Hepatitis B Virus Infection
G
L
View
102 12780567 Y200S
S
S
Hepatitis B Virus Infection
G
L
View
103 12780567 Y200Y
S
S
Hepatitis B Virus Infection
G
L
View
104 12780567 Y245H
P
P
Hepatitis B Virus Infection
G
L
View
105 12780567 Y245Y
P
P
Hepatitis B Virus Infection
G
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.