All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B Virus Infection-23408582

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	23408582	A181A	RT	P	Hepatitis B Virus Infection	D G L	View
2	23408582	A181V	RT	P	Hepatitis B Virus Infection	D G L	View
3	23408582	S202G	RT	P	Hepatitis B Virus Infection	D G L	View
4	23408582	T184SI	RT	P	Hepatitis B Virus Infection	G L	View
5	23408582	L180M	RT	P	Hepatitis B Virus Infection	G L	View
6	23408582	V173L	RT	P	Hepatitis B Virus Infection	G L	View
7	23408582	A181T	RT	P	Hepatitis B Virus Infection	D G L	View
8	23408582	W172X	S	S	Hepatitis B Virus Infection	G L	View
9	23408582	M204I	RT	P	Hepatitis B Virus Infection	D G L	View
10	23408582	M204V	RT	P	Hepatitis B Virus Infection	D G L	View
11	23408582	A194T	RT	P	Hepatitis B Virus Infection	G L	View
12	23408582	C221F	S	S	Hepatitis B Virus Infection	G L	View
13	23408582	C221G	S	S	Hepatitis B Virus Infection	G L	View
14	23408582	D134E	RT	P	Hepatitis B Virus Infection	G L	View
15	23408582	D144A	S	S	Hepatitis B Virus Infection	G I L	View
16	23408582	D144G	S	S	Hepatitis B Virus Infection	G I L	View
17	23408582	F220L	S	S	Hepatitis B Virus Infection	G L	View
18	23408582	G130N	S	S	Hepatitis B Virus Infection	G I L	View
19	23408582	G145A	S	S	Hepatitis B Virus Infection	G I L	View
20	23408582	I195M	S	S	Hepatitis B Virus Infection	G L	View
21	23408582	I233V	RT	P	Hepatitis B Virus Infection	G L	View
22	23408582	L109I	S	S	Hepatitis B Virus Infection	G I L	View
23	23408582	L173F	S	S	Hepatitis B Virus Infection	G L	View
24	23408582	L175F	S	S	Hepatitis B Virus Infection	G L	View
25	23408582	L216X	S	S	Hepatitis B Virus Infection	G L	View
26	23408582	L229F	RT	P	Hepatitis B Virus Infection	G L	View
27	23408582	L229M	RT	P	Hepatitis B Virus Infection	G L	View
28	23408582	L229V	RT	P	Hepatitis B Virus Infection	G L	View
29	23408582	L229W	RT	P	Hepatitis B Virus Infection	G L	View
30	23408582	L80V	RT	P	Hepatitis B Virus Infection	G L	View
31	23408582	M133I	S	S	Hepatitis B Virus Infection	G I L	View
32	23408582	M133L	S	S	Hepatitis B Virus Infection	G I L	View
33	23408582	M133T	S	S	Hepatitis B Virus Infection	G I L	View
34	23408582	P120S	S	S	Hepatitis B Virus Infection	G I L	View
35	23408582	P120T	S	S	Hepatitis B Virus Infection	G I L	View
36	23408582	P142L	S	S	Hepatitis B Virus Infection	G I L	View
37	23408582	Q215S	RT	P	Hepatitis B Virus Infection	G L	View
38	23408582	R138K	RT	P	Hepatitis B Virus Infection	G L	View
39	23408582	R153C	RT	P	Hepatitis B Virus Infection	G L	View
40	23408582	S117Y	RT	P	Hepatitis B Virus Infection	G L	View
41	23408582	S143L	S	S	Hepatitis B Virus Infection	G I L	View
42	23408582	S207R	S	S	Hepatitis B Virus Infection	G L	View
43	23408582	T126N	S	S	Hepatitis B Virus Infection	G I L	View
44	23408582	T126S	S	S	Hepatitis B Virus Infection	G I L	View
45	23408582	T127S	S	S	Hepatitis B Virus Infection	G I L	View
46	23408582	T128I	RT	P	Hepatitis B Virus Infection	G L	View
47	23408582	T128N	RT	P	Hepatitis B Virus Infection	G L	View
48	23408582	T184S	RT	P	Hepatitis B Virus Infection	G L	View
49	23408582	V142A	RT	P	Hepatitis B Virus Infection	G L	View
50	23408582	V142E	RT	P	Hepatitis B Virus Infection	G L	View
51	23408582	V142I	RT	P	Hepatitis B Virus Infection	G L	View
52	23408582	V191I	RT	P	Hepatitis B Virus Infection	G L	View
53	23408582	V207I	RT	P	Hepatitis B Virus Infection	G L	View
54	23408582	W182X	S	S	Hepatitis B Virus Infection	G L	View
55	23408582	W196X	S	S	Hepatitis B Virus Infection	G L	View
56	23408582	W196L	S	S	Hepatitis B Virus Infection	G L	View
57	23408582	W199X	S	S	Hepatitis B Virus Infection	G L	View
58	23408582	W199L	S	S	Hepatitis B Virus Infection	G L	View
59	23408582	Y134H	S	S	Hepatitis B Virus Infection	G I L	View
60	23408582	Y134N	S	S	Hepatitis B Virus Infection	G I L	View
61	23408582	Y134S	S	S	Hepatitis B Virus Infection	G I L	View
62	23408582	Y135F	RT	P	Hepatitis B Virus Infection	G L	View
63	23408582	Y141F	RT	P	Hepatitis B Virus Infection	G L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.