All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-23409946
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 23409946 S106X
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
2 23409946 Y111X
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
3 23409946 A181S
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
4 23409946 A181T
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
5 23409946 A181V
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
6 23409946 A194T
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
7 23409946 I169T
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
8 23409946 L180M
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
9 23409946 L80I
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
10 23409946 L80V
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
11 23409946 M204I
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
12 23409946 M204V
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
13 23409946 M250V
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
14 23409946 N236T
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
15 23409946 S202C
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
16 23409946 S202G
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
17 23409946 S202I
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
18 23409946 T184A
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
19 23409946 T184C
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
20 23409946 T184G
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
21 23409946 T184S
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
22 23409946 V173L
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
23 23409946 V103I
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
24 23409946 A113D
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
25 23409946 A113S
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
26 23409946 D134E
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
27 23409946 F122L
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
28 23409946 F221Y
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
29 23409946 H100Q
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
30 23409946 H121F
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
31 23409946 H121L
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
32 23409946 H121V
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
33 23409946 I163V
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
34 23409946 I187L
RT
P
Hepatitis B Virus Infection
D
G
S
C
L
View
35 23409946 I224V
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
36 23409946 I91L
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
37 23409946 L115V
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
38 23409946 L229F
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
39 23409946 N139E
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
40 23409946 N139Q
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
41 23409946 P237T
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
42 23409946 Q215E
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
43 23409946 Q215H
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
44 23409946 Q215P
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
45 23409946 Q215S
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
46 23409946 S109P
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
47 23409946 S109S
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
48 23409946 S213T
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
49 23409946 S78C
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
50 23409946 V142E
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
51 23409946 W153R
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
52 23409946 W79R
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
53 23409946 Y124D
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
54 23409946 Y124H
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
55 23409946 Y124N
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
56 23409946 Y126H
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
57 23409946 Y126R
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.