All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-24379746
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 24379746 G145A
S
S
Hepatitis B Virus Infection
G
R
L
View
2 24379746 I194V
S
S
Hepatitis B Virus Infection
G
R
L
View
3 24379746 N131T
S
S
Hepatitis B Virus Infection
G
R
L
View
4 24379746 S207N
S
S
Hepatitis B Virus Infection
G
R
L
View
5 24379746 S45A
S
S
Hepatitis B Virus Infection
G
R
L
View
6 24379746 S45T
S
S
Hepatitis B Virus Infection
G
R
L
View
7 24379746 A2891G
PreS
S
Hepatitis B Virus Infection
G
R
L
View
8 24379746 A2906G
PreS
S
Hepatitis B Virus Infection
G
R
L
View
9 24379746 A2946G
PreS
S
Hepatitis B Virus Infection
G
R
L
View
10 24379746 A2989C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
11 24379746 A3064G
PreS
S
Hepatitis B Virus Infection
G
R
L
View
12 24379746 A3092C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
13 24379746 A3111G
PreS
S
Hepatitis B Virus Infection
G
R
L
View
14 24379746 A3186G
PreS
S
Hepatitis B Virus Infection
G
R
L
View
15 24379746 A482C
S
S
Hepatitis B Virus Infection
G
R
L
View
16 24379746 A748G
S
S
Hepatitis B Virus Infection
G
R
L
View
17 24379746 A783G
S
S
Hepatitis B Virus Infection
G
R
L
View
18 24379746 C2875A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
19 24379746 C2985T
PreS
S
Hepatitis B Virus Infection
G
R
L
View
20 24379746 C3008A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
21 24379746 C3013A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
22 24379746 C3033A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
23 24379746 C3050T
PreS
S
Hepatitis B Virus Infection
G
R
L
View
24 24379746 C3091T
PreS
S
Hepatitis B Virus Infection
G
R
L
View
25 24379746 C3097A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
26 24379746 C3100T
PreS
S
Hepatitis B Virus Infection
G
R
L
View
27 24379746 C3116T
PreS
S
Hepatitis B Virus Infection
G
R
L
View
28 24379746 C3174T
PreS
S
Hepatitis B Virus Infection
G
R
L
View
29 24379746 C400A
S
S
Hepatitis B Virus Infection
G
R
L
View
30 24379746 C46A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
31 24379746 C52T
PreS
S
Hepatitis B Virus Infection
G
R
L
View
32 24379746 C7A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
33 24379746 G2927A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
34 24379746 G3000C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
35 24379746 G3075A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
36 24379746 G3120A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
37 24379746 G316A
S
S
Hepatitis B Virus Infection
G
R
L
View
38 24379746 G35A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
39 24379746 G372T
S
S
Hepatitis B Virus Infection
G
R
L
View
40 24379746 G6C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
41 24379746 G97A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
42 24379746 T109A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
43 24379746 T147C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
44 24379746 T150C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
45 24379746 T154C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
46 24379746 T2882C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
47 24379746 T2910C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
48 24379746 T2958C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
49 24379746 T3026C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
50 24379746 T3031G
PreS
S
Hepatitis B Virus Infection
G
R
L
View
51 24379746 T3051C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
52 24379746 T3066A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
53 24379746 T312C
S
S
Hepatitis B Virus Infection
G
R
L
View
54 24379746 T31C
PreS
S
Hepatitis B Virus Infection
G
R
L
View
55 24379746 T367C
S
S
Hepatitis B Virus Infection
G
R
L
View
56 24379746 T586C
S
S
Hepatitis B Virus Infection
G
R
L
View
57 24379746 T753A
S
S
Hepatitis B Virus Infection
G
R
L
View
58 24379746 F85C
S
S
Hepatitis B Virus Infection
G
R
L
View
59 24379746 G43R
S
S
Hepatitis B Virus Infection
G
R
L
View
60 24379746 I110L
S
S
Hepatitis B Virus Infection
G
R
L
View
61 24379746 K160R
S
S
Hepatitis B Virus Infection
G
R
L
View
62 24379746 L42A
S
S
Hepatitis B Virus Infection
G
R
L
View
63 24379746 L42I
S
S
Hepatitis B Virus Infection
G
R
L
View
64 24379746 L42S
S
S
Hepatitis B Virus Infection
G
R
L
View
65 24379746 L49P
S
S
Hepatitis B Virus Infection
G
R
L
View
66 24379746 N59S
S
S
Hepatitis B Virus Infection
G
R
L
View
67 24379746 P56Q
S
S
Hepatitis B Virus Infection
G
R
L
View
68 24379746 R73L
S
S
Hepatitis B Virus Infection
G
R
L
View
69 24379746 S113T
S
S
Hepatitis B Virus Infection
G
R
L
View
70 24379746 S64C
S
S
Hepatitis B Virus Infection
G
R
L
View
71 24379746 T114S
S
S
Hepatitis B Virus Infection
G
R
L
View
72 24379746 T126I
S
S
Hepatitis B Virus Infection
G
R
L
View
73 24379746 T143S
S
S
Hepatitis B Virus Infection
G
R
L
View
74 24379746 T57I
S
S
Hepatitis B Virus Infection
G
R
L
View
75 24379746 V47T
S
S
Hepatitis B Virus Infection
G
R
L
View
76 24379746 Y161F
S
S
Hepatitis B Virus Infection
G
R
L
View
77 24379746 Y200F
S
S
Hepatitis B Virus Infection
G
R
L
View
78 24379746 A54E
PreS
S
Hepatitis B Virus Infection
G
R
L
View
79 24379746 A90V
PreS
S
Hepatitis B Virus Infection
G
R
L
View
80 24379746 G16R
PreS
S
Hepatitis B Virus Infection
G
R
L
View
81 24379746 G27D
PreS
S
Hepatitis B Virus Infection
G
R
L
View
82 24379746 H56N
PreS
S
Hepatitis B Virus Infection
G
R
L
View
83 24379746 L173P
PreS
S
Hepatitis B Virus Infection
G
R
L
View
84 24379746 L84I
PreS
S
Hepatitis B Virus Infection
G
R
L
View
85 24379746 L85F
PreS
S
Hepatitis B Virus Infection
G
R
L
View
86 24379746 M12T
PreS
S
Hepatitis B Virus Infection
G
R
L
View
87 24379746 N15S
PreS
S
Hepatitis B Virus Infection
G
R
L
View
88 24379746 N20S
PreS
S
Hepatitis B Virus Infection
G
R
L
View
89 24379746 N48H
PreS
S
Hepatitis B Virus Infection
G
R
L
View
90 24379746 Q10K
PreS
S
Hepatitis B Virus Infection
G
R
L
View
91 24379746 Q51H
PreS
S
Hepatitis B Virus Infection
G
R
L
View
92 24379746 Q82S
PreS
S
Hepatitis B Virus Infection
G
R
L
View
93 24379746 S62A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
94 24379746 S6T
PreS
S
Hepatitis B Virus Infection
G
R
L
View
95 24379746 S73G
PreS
S
Hepatitis B Virus Infection
G
R
L
View
96 24379746 T68I
PreS
S
Hepatitis B Virus Infection
G
R
L
View
97 24379746 V172A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
98 24379746 V60A
PreS
S
Hepatitis B Virus Infection
G
R
L
View
99 24379746 A272T
P
P
Hepatitis B Virus Infection
G
R
L
View
100 24379746 C340S
P
P
Hepatitis B Virus Infection
G
R
L
View
101 24379746 E228A
P
P
Hepatitis B Virus Infection
G
R
L
View
102 24379746 E336K
P
P
Hepatitis B Virus Infection
G
R
L
View
103 24379746 F218L
P
P
Hepatitis B Virus Infection
G
R
L
View
104 24379746 H306N
P
P
Hepatitis B Virus Infection
G
R
L
View
105 24379746 I214V
P
P
Hepatitis B Virus Infection
G
R
L
View
106 24379746 I242S
P
P
Hepatitis B Virus Infection
G
R
L
View
107 24379746 L243I
P
P
Hepatitis B Virus Infection
G
R
L
View
108 24379746 L321F
P
P
Hepatitis B Virus Infection
G
R
L
View
109 24379746 L437I
P
P
Hepatitis B Virus Infection
G
R
L
View
110 24379746 M553V
P
P
Hepatitis B Virus Infection
G
R
L
View
111 24379746 P227S
P
P
Hepatitis B Virus Infection
G
R
L
View
112 24379746 P264H
P
P
Hepatitis B Virus Infection
G
R
L
View
113 24379746 P290S
P
P
Hepatitis B Virus Infection
G
R
L
View
114 24379746 P319T
P
P
Hepatitis B Virus Infection
G
R
L
View
115 24379746 Q253R
P
P
Hepatitis B Virus Infection
G
R
L
View
116 24379746 Q305H
P
P
Hepatitis B Virus Infection
G
R
L
View
117 24379746 R294G
P
P
Hepatitis B Virus Infection
G
R
L
View
118 24379746 R315Q
P
P
Hepatitis B Virus Infection
G
R
L
View
119 24379746 S202P
P
P
Hepatitis B Virus Infection
G
R
L
View
120 24379746 S234R
P
P
Hepatitis B Virus Infection
G
R
L
View
121 24379746 S249P
P
P
Hepatitis B Virus Infection
G
R
L
View
122 24379746 S254T
P
P
Hepatitis B Virus Infection
G
R
L
View
123 24379746 S262F
P
P
Hepatitis B Virus Infection
G
R
L
View
124 24379746 S314P
P
P
Hepatitis B Virus Infection
G
R
L
View
125 24379746 S340T
P
P
Hepatitis B Virus Infection
G
R
L
View
126 24379746 T190K
P
P
Hepatitis B Virus Infection
G
R
L
View
127 24379746 T236K
P
P
Hepatitis B Virus Infection
G
R
L
View
128 24379746 T265I
P
P
Hepatitis B Virus Infection
G
R
L
View
129 24379746 T269A
P
P
Hepatitis B Virus Infection
G
R
L
View
130 24379746 V232L
P
P
Hepatitis B Virus Infection
G
R
L
View
131 24379746 V257M
P
P
Hepatitis B Virus Infection
G
R
L
View
132 24379746 W499R
P
P
Hepatitis B Virus Infection
G
R
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.