All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-25333524
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 25333524 L213I
S
S
Hepatitis B Virus Infection
G
S
C
L
View
2 25333524 T147C
C
C
Hepatitis B Virus Infection
G
S
C
L
View
3 25333524 T1753C
BCP
Hepatitis B Virus Infection
G
S
C
L
View
4 25333524 G1764A
BCP
Hepatitis B Virus Infection
G
S
C
L
View
5 25333524 G1862T
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
6 25333524 I116L
C
C
Hepatitis B Virus Infection
G
S
C
L
View
7 25333524 P130Q
C
C
Hepatitis B Virus Infection
G
S
C
L
View
8 25333524 S98T
PreS1
S
Hepatitis B Virus Infection
G
S
C
L
View
9 25333524 T1858C
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
10 25333524 A1762T
BCP
Hepatitis B Virus Infection
G
S
C
L
View
11 25333524 A222T
RT
P
Hepatitis B Virus Infection
G
S
C
L
View
12 25333524 A1053G
EnhI
Hepatitis B Virus Infection
G
S
C
L
View
13 25333524 A1934T
C
C
Hepatitis B Virus Infection
G
S
C
L
View
14 25333524 A2246C
C
C
Hepatitis B Virus Infection
G
S
C
L
View
15 25333524 A2339T
C
C
Hepatitis B Virus Infection
G
S
C
L
View
16 25333524 C1653T
EnhII
Hepatitis B Virus Infection
G
S
C
L
View
17 25333524 C2100A
C
C
Hepatitis B Virus Infection
G
S
C
L
View
18 25333524 C2289A
C
C
Hepatitis B Virus Infection
G
S
C
L
View
19 25333524 C2340G
C
C
Hepatitis B Virus Infection
G
S
C
L
View
20 25333524 C528T
S
S
Hepatitis B Virus Infection
G
S
I
C
L
View
21 25333524 C534T
S
S
Hepatitis B Virus Infection
G
S
I
C
L
View
22 25333524 E113Q
C
C
Hepatitis B Virus Infection
G
S
C
L
View
23 25333524 F221Y
P
P
Hepatitis B Virus Infection
G
S
C
L
View
24 25333524 G1896A
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
25 25333524 G2237C
C
C
Hepatitis B Virus Infection
G
S
C
L
View
26 25333524 H94Y
X
X
Hepatitis B Virus Infection
G
S
C
L
View
27 25333524 I127T
X
X
Hepatitis B Virus Infection
G
S
C
L
View
28 25333524 K130M
X
X
Hepatitis B Virus Infection
G
S
C
L
View
29 25333524 L12V
P
P
Hepatitis B Virus Infection
G
S
C
L
View
30 25333524 S35T
C
C
Hepatitis B Virus Infection
G
S
C
L
View
31 25333524 T1050A
EnhI
Hepatitis B Virus Infection
G
S
C
L
View
32 25333524 T1050G
EnhI
Hepatitis B Virus Infection
G
S
C
L
View
33 25333524 T125M
S
S
Hepatitis B Virus Infection
G
S
I
C
L
View
34 25333524 T127L
S
S
Hepatitis B Virus Infection
G
S
I
C
L
View
35 25333524 T12S
C
C
Hepatitis B Virus Infection
G
S
C
L
View
36 25333524 T2003A
C
C
Hepatitis B Virus Infection
G
S
C
L
View
37 25333524 T3139A
PreS1
S
Hepatitis B Virus Infection
G
S
C
L
View
38 25333524 T67N
C
C
Hepatitis B Virus Infection
G
S
C
L
View
39 25333524 T791A
S
S
Hepatitis B Virus Infection
G
S
I
C
L
View
40 25333524 V131I
X
X
Hepatitis B Virus Infection
G
S
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.