All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-27882062
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 27882062 A168V
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
2 27882062 D144E
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
3 27882062 E164D
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
4 27882062 H124Y
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
5 27882062 L122F
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
6 27882062 L157M
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
7 27882062 N118D
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
8 27882062 N118T
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
9 27882062 P127L
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
10 27882062 P127T
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
11 27882062 Q129H
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
12 27882062 Q149K
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
13 27882062 S117G
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
14 27882062 S143L
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
15 27882062 T125M
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
16 27882062 A113S
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
17 27882062 A113V
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
18 27882062 G152R
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
19 27882062 L115V
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
20 27882062 L145M
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
21 27882062 L91I
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
22 27882062 M129L
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
23 27882062 N131D
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
24 27882062 N131S
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
25 27882062 N76D
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
26 27882062 Q125R
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
27 27882062 Q62R
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
28 27882062 R110G
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
29 27882062 S119P
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
30 27882062 S135Y
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
31 27882062 S180P
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
32 27882062 S78T
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
33 27882062 V112A
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
34 27882062 V173A
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
35 27882062 V173L
RT
P
Hepatitis B Virus Infection
G
R
S
C
L
View
36 27882062 C76Y
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
37 27882062 F85C
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
38 27882062 I110L
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
39 27882062 I92T
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
40 27882062 L104F
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
41 27882062 S54G
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
42 27882062 T123V
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
43 27882062 W165R
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.