All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-27998385
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 27998385 F134Y
S
S
Hepatitis B Virus Infection
G
I
L
 View
2 27998385 G145E
S
S
Hepatitis B Virus Infection
G
I
L
 View
3 27998385 Q129H
S
S
Hepatitis B Virus Infection
G
I
L
 View
4 27998385 S136Y
S
S
Hepatitis B Virus Infection
G
I
L
 View
5 27998385 A159G
S
S
Hepatitis B Virus Infection
G
I
L
 View
6 27998385 A1762T
BCP
Hepatitis B Virus Infection
G
L
 View
7 27998385 A1979G
C
C
Hepatitis B Virus Infection
G
L
 View
8 27998385 A1997T
C
C
Hepatitis B Virus Infection
G
L
 View
9 27998385 A2013T
C
C
Hepatitis B Virus Infection
G
L
 View
10 27998385 A2100C
C
C
Hepatitis B Virus Infection
G
L
 View
11 27998385 A2120G
C
C
Hepatitis B Virus Infection
G
L
 View
12 27998385 A2131C
C
C
Hepatitis B Virus Infection
G
L
 View
13 27998385 A2149C
C
C
Hepatitis B Virus Infection
G
L
 View
14 27998385 A2159G
C
C
Hepatitis B Virus Infection
G
L
 View
15 27998385 A2189C
C
C
Hepatitis B Virus Infection
G
L
 View
16 27998385 A2189T
C
C
Hepatitis B Virus Infection
G
L
 View
17 27998385 A2239C
C
C
Hepatitis B Virus Infection
G
L
 View
18 27998385 A2239T
C
C
Hepatitis B Virus Infection
G
L
 View
19 27998385 A2339G
C
C
Hepatitis B Virus Infection
G
L
 View
20 27998385 A98T
C
C
Hepatitis B Virus Infection
G
L
 View
21 27998385 C1913A
C
C
Hepatitis B Virus Infection
G
L
 View
22 27998385 C1914A
C
C
Hepatitis B Virus Infection
G
L
 View
23 27998385 C2004A
C
C
Hepatitis B Virus Infection
G
L
 View
24 27998385 C2048T
C
C
Hepatitis B Virus Infection
G
L
 View
25 27998385 C2063A
C
C
Hepatitis B Virus Infection
G
L
 View
26 27998385 C2198A
C
C
Hepatitis B Virus Infection
G
L
 View
27 27998385 C2246A
C
C
Hepatitis B Virus Infection
G
L
 View
28 27998385 C2288A
C
C
Hepatitis B Virus Infection
G
L
 View
29 27998385 C2289T
C
C
Hepatitis B Virus Infection
G
L
 View
30 27998385 C2290T
C
C
Hepatitis B Virus Infection
G
L
 View
31 27998385 C2304A
C
C
Hepatitis B Virus Infection
G
L
 View
32 27998385 C2337A
C
C
Hepatitis B Virus Infection
G
L
 View
33 27998385 C77L
C
C
Hepatitis B Virus Infection
G
L
 View
34 27998385 D107H
C
C
Hepatitis B Virus Infection
G
L
 View
35 27998385 E106D
C
C
Hepatitis B Virus Infection
G
L
 View
36 27998385 E112D
C
C
Hepatitis B Virus Infection
G
L
 View
37 27998385 E142D
C
C
Hepatitis B Virus Infection
G
L
 View
38 27998385 E69D
C
C
Hepatitis B Virus Infection
G
L
 View
39 27998385 E93D
C
C
Hepatitis B Virus Infection
G
L
 View
40 27998385 F220L
S
S
Hepatitis B Virus Infection
G
I
L
 View
41 27998385 G10R
S
S
Hepatitis B Virus Infection
G
I
L
 View
42 27998385 G1764A
BCP
Hepatitis B Virus Infection
G
L
 View
43 27998385 G182C
C
C
Hepatitis B Virus Infection
G
L
 View
44 27998385 G1896A
PreC
C
Hepatitis B Virus Infection
G
L
 View
45 27998385 G1915C
C
C
Hepatitis B Virus Infection
G
L
 View
46 27998385 G1937A
C
C
Hepatitis B Virus Infection
G
L
 View
47 27998385 G2020T
C
C
Hepatitis B Virus Infection
G
L
 View
48 27998385 G2043T
C
C
Hepatitis B Virus Infection
G
L
 View
49 27998385 G2088T
C
C
Hepatitis B Virus Infection
G
L
 View
50 27998385 G2092T
C
C
Hepatitis B Virus Infection
G
L
 View
51 27998385 G2105A
C
C
Hepatitis B Virus Infection
G
L
 View
52 27998385 G2121T
C
C
Hepatitis B Virus Infection
G
L
 View
53 27998385 G2132C
C
C
Hepatitis B Virus Infection
G
L
 View
54 27998385 G2160A
C
C
Hepatitis B Virus Infection
G
L
 View
55 27998385 G2171A
C
C
Hepatitis B Virus Infection
G
L
 View
56 27998385 G2345A
C
C
Hepatitis B Virus Infection
G
L
 View
57 27998385 G2352A
C
C
Hepatitis B Virus Infection
G
L
 View
58 27998385 G2357T
C
C
Hepatitis B Virus Infection
G
L
 View
59 27998385 G44E
S
S
Hepatitis B Virus Infection
G
I
L
 View
60 27998385 G92V
C
C
Hepatitis B Virus Infection
G
L
 View
61 27998385 I126F
C
C
Hepatitis B Virus Infection
G
L
 View
62 27998385 I218T
S
S
Hepatitis B Virus Infection
G
I
L
 View
63 27998385 I56V
C
C
Hepatitis B Virus Infection
G
L
 View
64 27998385 I68T
S
S
Hepatitis B Virus Infection
G
I
L
 View
65 27998385 L105M
C
C
Hepatitis B Virus Infection
G
L
 View
66 27998385 L129I
C
C
Hepatitis B Virus Infection
G
L
 View
67 27998385 L145I
C
C
Hepatitis B Virus Infection
G
L
 View
68 27998385 L213I
S
S
Hepatitis B Virus Infection
G
I
L
 View
69 27998385 L216X
S
S
Hepatitis B Virus Infection
G
I
L
 View
70 27998385 L21S
S
S
Hepatitis B Virus Infection
G
I
L
 View
71 27998385 L66Q
C
C
Hepatitis B Virus Infection
G
L
 View
72 27998385 L84I
C
C
Hepatitis B Virus Infection
G
L
 View
73 27998385 M213I
S
S
Hepatitis B Virus Infection
G
I
L
 View
74 27998385 N207S
S
S
Hepatitis B Virus Infection
G
I
L
 View
75 27998385 N96T
C
C
Hepatitis B Virus Infection
G
L
 View
76 27998385 P159I
C
C
Hepatitis B Virus Infection
G
L
 View
77 27998385 P159T
C
C
Hepatitis B Virus Infection
G
L
 View
78 27998385 P164Q
C
C
Hepatitis B Virus Infection
G
L
 View
79 27998385 P188H
S
S
Hepatitis B Virus Infection
G
I
L
 View
80 27998385 P203R
S
S
Hepatitis B Virus Infection
G
I
L
 View
81 27998385 P34H
C
C
Hepatitis B Virus Infection
G
L
 View
82 27998385 P34T
C
C
Hepatitis B Virus Infection
G
L
 View
83 27998385 P46T
S
S
Hepatitis B Virus Infection
G
I
L
 View
84 27998385 P79S
C
C
Hepatitis B Virus Infection
G
L
 View
85 27998385 R180Q
C
C
Hepatitis B Virus Infection
G
L
 View
86 27998385 S103G
C
C
Hepatitis B Virus Infection
G
L
 View
87 27998385 S103V
C
C
Hepatitis B Virus Infection
G
L
 View
88 27998385 S116G
C
C
Hepatitis B Virus Infection
G
L
 View
89 27998385 S116N
C
C
Hepatitis B Virus Infection
G
L
 View
90 27998385 S184P
C
C
Hepatitis B Virus Infection
G
L
 View
91 27998385 S204R
S
S
Hepatitis B Virus Infection
G
I
L
 View
92 27998385 S210R
S
S
Hepatitis B Virus Infection
G
I
L
 View
93 27998385 S41T
C
C
Hepatitis B Virus Infection
G
L
 View
94 27998385 S50A
C
C
Hepatitis B Virus Infection
G
L
 View
95 27998385 S53L
S
S
Hepatitis B Virus Infection
G
I
L
 View
96 27998385 S61L
S
S
Hepatitis B Virus Infection
G
I
L
 View
97 27998385 S64N
C
C
Hepatitis B Virus Infection
G
L
 View
98 27998385 S64T
C
C
Hepatitis B Virus Infection
G
L
 View
99 27998385 T123A
S
S
Hepatitis B Virus Infection
G
I
L
 View
100 27998385 T175N
C
C
Hepatitis B Virus Infection
G
L
 View
101 27998385 T176A
C
C
Hepatitis B Virus Infection
G
L
 View
102 27998385 T1934A
C
C
Hepatitis B Virus Infection
G
L
 View
103 27998385 T1961G
C
C
Hepatitis B Virus Infection
G
L
 View
104 27998385 T1981A
C
C
Hepatitis B Virus Infection
G
L
 View
105 27998385 T2003A
C
C
Hepatitis B Virus Infection
G
L
 View
106 27998385 T2010A
C
C
Hepatitis B Virus Infection
G
L
 View
107 27998385 T2012C
C
C
Hepatitis B Virus Infection
G
L
 View
108 27998385 T2042C
C
C
Hepatitis B Virus Infection
G
L
 View
109 27998385 T2101A
C
C
Hepatitis B Virus Infection
G
L
 View
110 27998385 T2122A
C
C
Hepatitis B Virus Infection
G
L
 View
111 27998385 T2126A
C
C
Hepatitis B Virus Infection
G
L
 View
112 27998385 T2172C
C
C
Hepatitis B Virus Infection
G
L
 View
113 27998385 T2363C
C
C
Hepatitis B Virus Infection
G
L
 View
114 27998385 T47A
S
S
Hepatitis B Virus Infection
G
I
L
 View
115 27998385 T47K
S
S
Hepatitis B Virus Infection
G
I
L
 View
116 27998385 T62S
C
C
Hepatitis B Virus Infection
G
L
 View
117 27998385 V120T
C
C
Hepatitis B Virus Infection
G
L
 View
118 27998385 V14A
S
S
Hepatitis B Virus Infection
G
I
L
 View
119 27998385 V168A
S
S
Hepatitis B Virus Infection
G
I
L
 View
120 27998385 V178I
C
C
Hepatitis B Virus Infection
G
L
 View
121 27998385 V184A
S
S
Hepatitis B Virus Infection
G
I
L
 View
122 27998385 V194A
S
S
Hepatitis B Virus Infection
G
I
L
 View
123 27998385 V42T
C
C
Hepatitis B Virus Infection
G
L
 View
124 27998385 W28X
PreC
C
Hepatitis B Virus Infection
G
L
 View
125 27998385 Y67F
C
C
Hepatitis B Virus Infection
G
L
 View
126 27998385 Y67H
C
C
Hepatitis B Virus Infection
G
L
 View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.