All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-28939157
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 28939157 C221G
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
2 28939157 C221R
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
3 28939157 C221S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
4 28939157 C221Y
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
5 28939157 C76F
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
6 28939157 C76S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
7 28939157 C76Y
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
8 28939157 F200C
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
9 28939157 F200Y
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
10 28939157 G44E
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
11 28939157 I68T
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
12 28939157 I92S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
13 28939157 I92T
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
14 28939157 L30P
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
15 28939157 L30Q
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
16 28939157 L30R
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
17 28939157 L42E
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
18 28939157 L42P
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
19 28939157 L42R
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
20 28939157 L8F
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
21 28939157 L8H
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
22 28939157 L8P
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
23 28939157 N40S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
24 28939157 P127A
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
25 28939157 P127S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
26 28939157 P127T
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
27 28939157 Q129K
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
28 28939157 R24G
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
29 28939157 R24K
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
30 28939157 S204N
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
31 28939157 S204R
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
32 28939157 S210N
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
33 28939157 S210R
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
34 28939157 S53L
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
35 28939157 S53P
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
36 28939157 S59N
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
37 28939157 V177A
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
38 28939157 A126S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
39 28939157 A5S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
40 28939157 A5T
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
41 28939157 G10E
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
42 28939157 G10Q
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
43 28939157 G10R
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
44 28939157 G145A
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
45 28939157 G145R
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
46 28939157 I126T
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
47 28939157 L175F
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
48 28939157 L175S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
49 28939157 L213I
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
50 28939157 L213S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
51 28939157 L21S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
52 28939157 L98P
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
53 28939157 L98V
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
54 28939157 N131A
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
55 28939157 N131I
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
56 28939157 N3S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
57 28939157 Q129H
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
58 28939157 Q129L
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
59 28939157 Q129R
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
60 28939157 S126N
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
61 28939157 S126V
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
62 28939157 T131A
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
63 28939157 T131I
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
64 28939157 T131N
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
65 28939157 T131P
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
66 28939157 T47A
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
67 28939157 T47K
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
68 28939157 T47V
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
69 28939157 T5A
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
70 28939157 V224A
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
71 28939157 V224G
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
72 28939157 S126T
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
73 28939157 I126N
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
74 28939157 I126V
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
75 28939157 T126S
S
S
Hepatitis B Virus Infection
G
R
S
I
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.