All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-30570771
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 30570771 P127T
S
S
Hepatitis B Virus Infection
S
I
L
View
2 30570771 T125M
S
S
Hepatitis B Virus Infection
S
I
L
View
3 30570771 A223S
RT
P
Hepatitis B Virus Infection
G
S
L
View
4 30570771 L34F
X
X
Hepatitis B Virus Infection
G
S
L
View
5 30570771 S29P
X
X
Hepatitis B Virus Infection
G
S
L
View
6 30570771 113_115del
S
S
Hepatitis B Virus Infection
G
S
L
View
7 30570771 A38E
RT
P
Hepatitis B Virus Infection
G
S
L
View
8 30570771 C183L
S
S
Hepatitis B Virus Infection
G
S
L
View
9 30570771 C19F
S
S
Hepatitis B Virus Infection
G
S
L
View
10 30570771 D144E
S
S
Hepatitis B Virus Infection
G
S
I
L
View
11 30570771 D31N
RT
P
Hepatitis B Virus Infection
G
S
L
View
12 30570771 F122V
RT
P
Hepatitis B Virus Infection
G
S
L
View
13 30570771 F148Y
RT
P
Hepatitis B Virus Infection
G
S
L
View
14 30570771 F170L
S
S
Hepatitis B Virus Infection
G
S
L
View
15 30570771 F83V
S
S
Hepatitis B Virus Infection
G
S
L
View
16 30570771 F8L
S
S
Hepatitis B Virus Infection
G
S
L
View
17 30570771 G44A
S
S
Hepatitis B Virus Infection
G
S
L
View
18 30570771 H12Q
RT
P
Hepatitis B Virus Infection
G
S
L
View
19 30570771 H197R
RT
P
Hepatitis B Virus Infection
G
S
L
View
20 30570771 H216S
RT
P
Hepatitis B Virus Infection
G
S
L
View
21 30570771 H35Q
RT
P
Hepatitis B Virus Infection
G
S
L
View
22 30570771 I110L
S
S
Hepatitis B Virus Infection
G
S
L
View
23 30570771 I16T
RT
P
Hepatitis B Virus Infection
G
S
L
View
24 30570771 I28M
S
S
Hepatitis B Virus Infection
G
S
L
View
25 30570771 I4S
S
S
Hepatitis B Virus Infection
G
S
L
View
26 30570771 I68N
S
S
Hepatitis B Virus Infection
G
S
L
View
27 30570771 I91C
RT
P
Hepatitis B Virus Infection
G
S
L
View
28 30570771 I91R
RT
P
Hepatitis B Virus Infection
G
S
L
View
29 30570771 I91S
RT
P
Hepatitis B Virus Infection
G
S
L
View
30 30570771 L145M
RT
P
Hepatitis B Virus Infection
G
S
L
View
31 30570771 L151F
RT
P
Hepatitis B Virus Infection
G
S
L
View
32 30570771 L179V
RT
P
Hepatitis B Virus Infection
G
S
L
View
33 30570771 L91I
RT
P
Hepatitis B Virus Infection
G
S
L
View
34 30570771 L97F
S
S
Hepatitis B Virus Infection
G
S
L
View
35 30570771 L98V
S
S
Hepatitis B Virus Infection
G
S
L
View
36 30570771 M198I
S
S
Hepatitis B Virus Infection
G
S
L
View
37 30570771 N118T
RT
P
Hepatitis B Virus Infection
G
S
L
View
38 30570771 N53K
RT
P
Hepatitis B Virus Infection
G
S
L
View
39 30570771 N76D
RT
P
Hepatitis B Virus Infection
G
S
L
View
40 30570771 N76K
RT
P
Hepatitis B Virus Infection
G
S
L
View
41 30570771 P67Q
S
S
Hepatitis B Virus Infection
G
S
L
View
42 30570771 Q130P
RT
P
Hepatitis B Virus Infection
G
S
L
View
43 30570771 Q149K
RT
P
Hepatitis B Virus Infection
G
S
L
View
44 30570771 Q215H
RT
P
Hepatitis B Virus Infection
G
S
L
View
45 30570771 Q30K
S
S
Hepatitis B Virus Infection
G
S
L
View
46 30570771 R153G
RT
P
Hepatitis B Virus Infection
G
S
L
View
47 30570771 R192S
RT
P
Hepatitis B Virus Infection
G
S
L
View
48 30570771 S105F
RT
P
Hepatitis B Virus Infection
G
S
L
View
49 30570771 S106C
RT
P
Hepatitis B Virus Infection
G
S
L
View
50 30570771 S106F
RT
P
Hepatitis B Virus Infection
G
S
L
View
51 30570771 S117N
S
S
Hepatitis B Virus Infection
G
S
L
View
52 30570771 S135Y
RT
P
Hepatitis B Virus Infection
G
S
L
View
53 30570771 S140T
S
S
Hepatitis B Virus Infection
G
S
I
L
View
54 30570771 S204K
S
S
Hepatitis B Virus Infection
G
S
L
View
55 30570771 S207N
S
S
Hepatitis B Virus Infection
G
S
L
View
56 30570771 S213T
RT
P
Hepatitis B Virus Infection
G
S
L
View
57 30570771 S85F
RT
P
Hepatitis B Virus Infection
G
S
L
View
58 30570771 T116N
S
S
Hepatitis B Virus Infection
G
S
L
View
59 30570771 T128S
RT
P
Hepatitis B Virus Infection
G
S
L
View
60 30570771 T143M
S
S
Hepatitis B Virus Infection
G
S
I
L
View
61 30570771 T189A
S
S
Hepatitis B Virus Infection
G
S
L
View
62 30570771 T23I
S
S
Hepatitis B Virus Infection
G
S
L
View
63 30570771 T27K
S
S
Hepatitis B Virus Infection
G
S
L
View
64 30570771 T37A
RT
P
Hepatitis B Virus Infection
G
S
L
View
65 30570771 T45N
S
S
Hepatitis B Virus Infection
G
S
L
View
66 30570771 V18A
S
S
Hepatitis B Virus Infection
G
S
L
View
67 30570771 V207L
RT
P
Hepatitis B Virus Infection
G
S
L
View
68 30570771 Y126H
RT
P
Hepatitis B Virus Infection
G
S
L
View
69 30570771 Y54H
RT
P
Hepatitis B Virus Infection
G
S
L
View
70 30570771 K130M
X
X
Hepatitis B Virus Infection
S
L
View
71 30570771 V131I
X
X
Hepatitis B Virus Infection
S
L
View
72 30570771 G1896A
PreC
C
Hepatitis B Virus Infection
G
S
L
View
73 30570771 A1762T
BCP
Hepatitis B Virus Infection
G
S
L
View
74 30570771 G1764A
BCP
Hepatitis B Virus Infection
G
S
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.