All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-35715756
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 35715756 A1762T
BCP
Hepatitis B Virus Infection
G
S
C
L
View
2 35715756 G145R
S
S
Hepatitis B Virus Infection
G
S
I
C
L
View
3 35715756 G1764T
BCP
Hepatitis B Virus Infection
G
S
C
L
View
4 35715756 G1896A
PreC;C
C
Hepatitis B Virus Infection
G
S
C
L
View
5 35715756 G1899A
PreC;C
C
Hepatitis B Virus Infection
G
S
C
L
View
6 35715756 P120T
S
S
Hepatitis B Virus Infection
G
S
I
C
L
View
7 35715756 A109T
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
8 35715756 A109V
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
9 35715756 A160G
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
10 35715756 A160P
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
11 35715756 A168V
S
S
Hepatitis B Virus Infection
G
S
C
L
View
12 35715756 A1727G
BCP
Hepatitis B Virus Infection
G
S
C
L
View
13 35715756 A1752C
BCP
Hepatitis B Virus Infection
G
S
C
L
View
14 35715756 A1775C
BCP
Hepatitis B Virus Infection
G
S
C
L
View
15 35715756 A1775G
BCP
Hepatitis B Virus Infection
G
S
C
L
View
16 35715756 C1766G
BCP
Hepatitis B Virus Infection
G
S
C
L
View
17 35715756 C1773T
BCP
Hepatitis B Virus Infection
G
S
C
L
View
18 35715756 C77G
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
19 35715756 C7R
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
20 35715756 E106Q
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
21 35715756 E164G
S
S
Hepatitis B Virus Infection
G
S
C
L
View
22 35715756 E93D
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
23 35715756 F53Y
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
24 35715756 F85C
S
S
Hepatitis B Virus Infection
G
S
C
L
View
25 35715756 F93C
S
S
Hepatitis B Virus Infection
G
S
C
L
View
26 35715756 G103A
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
27 35715756 G130E
S
S
Hepatitis B Virus Infection
G
S
C
L
View
28 35715756 G159A
S
S
Hepatitis B Virus Infection
G
S
C
L
View
29 35715756 G159V
S
S
Hepatitis B Virus Infection
G
S
C
L
View
30 35715756 G29D
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
31 35715756 I127T
X
X
Hepatitis B Virus Infection
G
S
C
L
View
32 35715756 I145L
S
S
Hepatitis B Virus Infection
G
S
C
L
View
33 35715756 I92T
S
S
Hepatitis B Virus Infection
G
S
C
L
View
34 35715756 K130I
X
X
Hepatitis B Virus Infection
G
S
C
L
View
35 35715756 K130M
X
X
Hepatitis B Virus Infection
G
S
C
L
View
36 35715756 L109P
S
S
Hepatitis B Virus Infection
G
S
C
L
View
37 35715756 L113Q
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
38 35715756 L94S
S
S
Hepatitis B Virus Infection
G
S
C
L
View
39 35715756 M122A
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
40 35715756 M122V
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
41 35715756 M125T
S
S
Hepatitis B Virus Infection
G
S
C
L
View
42 35715756 N121T
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
43 35715756 P159Q
S
S
Hepatitis B Virus Infection
G
S
C
L
View
44 35715756 P164T
S
S
Hepatitis B Virus Infection
G
S
C
L
View
45 35715756 P185S
BCP
Hepatitis B Virus Infection
G
S
C
L
View
46 35715756 R180Q
BCP
Hepatitis B Virus Infection
G
S
C
L
View
47 35715756 S116G
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
48 35715756 S50A
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
49 35715756 S64A
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
50 35715756 S78T
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
51 35715756 T120S
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
52 35715756 T127P
S
S
Hepatitis B Virus Infection
G
S
C
L
View
53 35715756 T143I
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
54 35715756 T1753C
BCP
Hepatitis B Virus Infection
G
S
C
L
View
55 35715756 T1758C
BCP
Hepatitis B Virus Infection
G
S
C
L
View
56 35715756 T176C
BCP
Hepatitis B Virus Infection
G
S
C
L
View
57 35715756 T1832C
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
58 35715756 T96I
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
59 35715756 V131I
X
X
Hepatitis B Virus Infection
G
S
C
L
View
60 35715756 V131L
X
X
Hepatitis B Virus Infection
G
S
C
L
View
61 35715756 V17F
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
62 35715756 V96G
S
S
Hepatitis B Virus Infection
G
S
C
L
View
63 35715756 W165R
S
S
Hepatitis B Virus Infection
G
S
C
L
View
64 35715756 W28X
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
65 35715756 Y67F
PreC
C
Hepatitis B Virus Infection
G
S
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.