All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-38004634
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 38004634 L180M
P
P
Hepatitis B Virus Infection
D
G
R
S
C
L
View
2 38004634 S202G
P
P
Hepatitis B Virus Infection
D
G
R
S
C
L
View
3 38004634 132F
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
4 38004634 A166T
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
5 38004634 A166V
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
6 38004634 A17E
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
7 38004634 A194V
P
P
Hepatitis B Virus Infection
D
G
R
S
C
L
View
8 38004634 A223S
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
9 38004634 C256
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
10 38004634 C262S
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
11 38004634 C76Y
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
12 38004634 D263E
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
13 38004634 E271D
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
14 38004634 E718K
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
15 38004634 H124Y
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
16 38004634 H160P
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
17 38004634 I195M
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
18 38004634 I266R
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
19 38004634 L145M
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
20 38004634 L231S
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
21 38004634 L231W
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
22 38004634 L712
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
23 38004634 M204I
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
24 38004634 M204V
P
P
Hepatitis B Virus Infection
D
G
R
S
C
L
View
25 38004634 M699I
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
26 38004634 N131D
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
27 38004634 N236T
P
P
Hepatitis B Virus Infection
D
G
R
S
C
L
View
28 38004634 N238H
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
29 38004634 N238T
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
30 38004634 N248H
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
31 38004634 N459Y
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
32 38004634 P130Q
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
33 38004634 P142L
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
34 38004634 P153K
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
35 38004634 P153S
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
36 38004634 P161S
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
37 38004634 Q129H
S
S
Hepatitis B Virus Infection
G
R
S
I
C
L
View
38 38004634 Q181K
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
39 38004634 Q181R
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
40 38004634 Q215P
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
41 38004634 R705P
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
42 38004634 S189Q
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
43 38004634 S193L
S
S
Hepatitis B Virus Infection
D
G
R
S
I
C
L
View
44 38004634 S709L
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
45 38004634 S709R
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
46 38004634 T184A
P
P
Hepatitis B Virus Infection
D
G
R
S
C
L
View
47 38004634 T322S
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
48 38004634 T707P
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
49 38004634 V173M
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
50 38004634 V184R
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
51 38004634 V190M
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
52 38004634 V191G
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
53 38004634 V253I
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
54 38004634 V278I
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
55 38004634 W156C
S
S
Hepatitis B Virus Infection
G
R
S
C
L
View
56 38004634 Y135S
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
57 38004634 Y257H
P
P
Hepatitis B Virus Infection
G
R
S
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.