All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B Virus Infection-40283226

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	40283226	A128V	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
2	40283226	A181C	RT	P	Hepatitis B Virus Infection	G S C L	View
3	40283226	A181T	RT	P	Hepatitis B Virus Infection	G S C L	View
4	40283226	D134E	RT	P	Hepatitis B Virus Infection	G S C L	View
5	40283226	D144A	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
6	40283226	D144E	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
7	40283226	G130D	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
8	40283226	G130N	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
9	40283226	G130R	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
10	40283226	G145A	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
11	40283226	G145R	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
12	40283226	I169L	RT	P	Hepatitis B Virus Infection	G S C L	View
13	40283226	I169T	RT	P	Hepatitis B Virus Infection	G S C L	View
14	40283226	I233V	RT	P	Hepatitis B Virus Infection	G S C L	View
15	40283226	L109I	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
16	40283226	L109L	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
17	40283226	L180M	RT	P	Hepatitis B Virus Infection	G S C L	View
18	40283226	L82M	RT	P	Hepatitis B Virus Infection	G S C L	View
19	40283226	M133I	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
20	40283226	M133L	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
21	40283226	M133T	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
22	40283226	M204I	RT	P	Hepatitis B Virus Infection	G S C L	View
23	40283226	M204V	RT	P	Hepatitis B Virus Infection	G S C L	View
24	40283226	M250L	RT	P	Hepatitis B Virus Infection	G S C L	View
25	40283226	M250V	RT	P	Hepatitis B Virus Infection	G S C L	View
26	40283226	N236D	RT	P	Hepatitis B Virus Infection	G S C L	View
27	40283226	N236T	RT	P	Hepatitis B Virus Infection	G S C L	View
28	40283226	P120A	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
29	40283226	P120L	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
30	40283226	P120Q	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
31	40283226	P120S	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
32	40283226	P120T	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
33	40283226	P127A	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
34	40283226	P127L	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
35	40283226	P127T	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
36	40283226	P142L	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
37	40283226	Q129R	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
38	40283226	S202G	RT	P	Hepatitis B Virus Infection	G S C L	View
39	40283226	S53N	RT	P	Hepatitis B Virus Infection	G S C L	View
40	40283226	T118K	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
41	40283226	T126I	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
42	40283226	T126N	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
43	40283226	T131N	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
44	40283226	T184A	RT	P	Hepatitis B Virus Infection	G S C L	View
45	40283226	T184I	RT	P	Hepatitis B Virus Infection	G S C L	View
46	40283226	T184S	RT	P	Hepatitis B Virus Infection	G S C L	View
47	40283226	T38A	RT	P	Hepatitis B Virus Infection	G S C L	View
48	40283226	T54N	RT	P	Hepatitis B Virus Infection	G S C L	View
49	40283226	V173L	RT	P	Hepatitis B Virus Infection	G S C L	View
50	40283226	V173M	RT	P	Hepatitis B Virus Infection	G S C L	View
51	40283226	Y100C	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
52	40283226	Y124H	RT	P	Hepatitis B Virus Infection	G S C L	View
53	40283226	Y134H	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
54	40283226	Y134N	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
55	40283226	Y134S	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View
56	40283226	Y134V	PreS;S	S	Hepatitis B Virus Infection	G S I C L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.