All Curated Mutation Sites in HCV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HCV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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Click the button below to quickly view the viral genes/regions/protein for mutation

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5'UTR
  
C
  
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p7
  
Protease
  

Keyword: C
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 20175782 G435C
C
Core
Carcinoma, Hepatocellular
G
 View
2 20175782 G481A
C
Core
Carcinoma, Hepatocellular
G
 View
3 21799903 K861E
C
Core
HCV Infection
View
4 21799903 K888E
C
Core
HCV Infection
View
5 37384719 T49A
C
Core
HCV Infection
R
S
L
 View
6 37384719 T49V
C
Core
HCV Infection
R
S
L
 View
7 23940646 F172C
C
Core
HCV Infection
View
8 23940646 P173S
C
Core
HCV Infection
View
9 36680226 R70H
C
Core
HCV Infection
R
S
C
L
 View
10 38103659 L91M
C
Core
HCV Infection
View
11 38103659 R70H
C
Core
HCV Infection
View
12 38103659 R70Q
C
Core
HCV Infection
View
13 20175782 K10Q
C
Core
Carcinoma, Hepatocellular
G
 View
14 20175782 M91L
C
Core
Carcinoma, Hepatocellular
G
 View
15 20175782 R70Q
C
Core
Carcinoma, Hepatocellular
G
 View
16 27163636 R70H
C
Core
Carcinoma, Hepatocellular
HCV Infection
G
 View
17 27163636 R70Q
C
Core
Carcinoma, Hepatocellular
HCV Infection
G
 View
18 36680226 C91M
C
Core
HCV Infection
G
R
S
C
L
 View
19 36680226 R70P
C
Core
HCV Infection
G
R
S
C
L
 View
20 36680226 R70Q
C
Core
HCV Infection
G
R
S
C
L
 View
21 22995142 R70Q
C
Core
HCV Infection
G
S
L
 View
22 22995142 C91M
C
Core
HCV Infection
G
S
L
 View
23 22995142 L91M
C
Core
HCV Infection
G
S
L
 View
24 31589628 R70Q
C
Core
HCV Infection
G
R
S
L
 View
25 31589628 M91L
C
Core
HCV Infection
G
R
S
L
 View
26 29577052 R70Q
C
Core
HCV Infection
G
R
I
L
 View
27 29577052 R70H
C
Core
HCV Infection
G
R
I
L
 View
28 29577052 L91M
C
Core
HCV Infection
G
R
I
L
 View
29 27729747 L91M
C
Core
HCV Infection
G
 View
30 27729747 R70H
C
Core
HCV Infection
G
 View
31 27729747 R70Q
C
Core
HCV Infection
G
 View
32 36680226 L91M
C
Core
HCV Infection
G
R
S
C
L
 View
33 33246391 A77G
C
Core
HCV Infection
G
R
L
 View
34 33246391 G145R
C
Core
HCV Infection
G
R
L
 View
35 33246391 G60E
C
Core
HCV Infection
G
R
L
 View
36 33246391 G90S
C
Core
HCV Infection
G
R
L
 View
37 33246391 L91C
C
Core
HCV Infection
G
R
L
 View
38 33246391 N105A
C
Core
HCV Infection
G
R
L
 View
39 33246391 N110I
C
Core
HCV Infection
G
R
L
 View
40 33246391 P108A
C
Core
HCV Infection
G
R
L
 View
41 33246391 R46C
C
Core
HCV Infection
G
R
L
 View
42 33246391 R70Q
C
Core
HCV Infection
G
R
L
 View
43 33246391 S105A
C
Core
HCV Infection
G
R
L
 View
44 33246391 S116V
C
Core
HCV Infection
G
R
L
 View
45 25994168 A48T
C
Core
HCV Infection
G
S
 View
46 25994168 T49A
C
Core
HCV Infection
G
S
 View
47 25994168 T49P
C
Core
HCV Infection
G
S
 View
48 24708767 G114R
C
Core
HCV Infection
G
S
C
L
 View
49 24708767 S146G
C
Core
HCV Infection
G
S
C
L
 View
50 24708767 K74R
C
Core
HCV Infection
G
S
C
L
 View
51 24708767 Q12K
C
Core
HCV Infection
G
S
C
L
 View
52 24708767 R70Q
C
Core
HCV Infection
G
S
C
L
 View
53 24708767 T20M
C
Core
HCV Infection
G
S
C
L
 View
54 27630727 R70H
C
Core
Hepatitis C, Chronic
G
C
L
 View
55 27630727 R70L
C
Core
Hepatitis C, Chronic
G
C
L
 View
56 27630727 R70P
C
Core
Hepatitis C, Chronic
G
C
L
 View
57 27630727 R70Q
C
Core
Hepatitis C, Chronic
G
C
L
 View
58 26684004 R70H
C
Core
Hepatitis C, Chronic
D
G
C
L
 View
59 26684004 R70Q
C
Core
Hepatitis C, Chronic
D
G
C
L
 View
60 27313635 M91L
C
Core
Hepatitis C, Chronic
G
L
 View
61 27313635 R43K
C
Core
Hepatitis C, Chronic
G
L
 View
62 27313635 R70Q
C
Core
Hepatitis C, Chronic
G
L
 View
63 27313635 S106N
C
Core
Hepatitis C, Chronic
G
L
 View
64 20175782 A28C
C
Core
Carcinoma, Hepatocellular
G
 View
65 35763545 I30T
C
Core
Cell line
G
 View
66 36424447 K74T
C
Core
Cell line
View
67 26339783 A147V
C
Core
Cell line
R
 View
68 26339783 A75S
C
Core
Cell line
R
 View
69 26339783 E20Q
C
Core
Cell line
R
 View
70 26339783 F172C
C
Core
Cell line
R
 View
71 26339783 L91C
C
Core
Cell line
R
 View
72 26339783 P173S
C
Core
Cell line
R
 View
73 26339783 R81Y
C
Core
Cell line
R
 View
74 26339783 S145G
C
Core
Cell line
R
 View
75 26339783 T48A
C
Core
Cell line
R
 View
76 26339783 V151L
C
Core
Cell line
R
 View
77 24625789 A150T
C
Core
Cell line
View
78 24625789 A180V
C
Core
Cell line
View
79 24625789 E159V
C
Core
Cell line
View
80 24625789 E54G
C
Core
Cell line
View
81 24625789 G146R
C
Core
Cell line
View
82 24625789 I30T
C
Core
Cell line
View
83 24625789 I65V
C
Core
Cell line
View
84 24625789 K23M
C
Core
Cell line
View
85 24625789 L133S
C
Core
Cell line
View
86 24625789 L185S
C
Core
Cell line
View
87 24625789 L91P
C
Core
Cell line
View
88 24625789 M134T
C
Core
Cell line
View
89 24625789 N118I
C
Core
Cell line
View
90 24625789 N163D
C
Core
Cell line
View
91 24625789 P170A
C
Core
Cell line
View
92 24625789 Q20R
C
Core
Cell line
View
93 24625789 S450P
C
Core
Cell line
View
94 24625789 S53P
C
Core
Cell line
View
95 24625789 S56P
C
Core
Cell line
View
96 24625789 T11S
C
Core
Cell line
View
97 24625789 T125S
C
Core
Cell line
View
98 24625789 T52A
C
Core
Cell line
View
99 24625789 V31A
C
Core
Cell line
View
100 24625789 V46A
C
Core
Cell line
View
101 24625789 W76R
C
Core
Cell line
View
102 24533158 K51A
C
Core
Cell line
View
103 24533158 R50A
C
Core
Cell line
View
104 24533158 R59A
C
Core
Cell line
View
105 24533158 R62A
C
Core
Cell line
View
106 20175782 A271C
C
Core
Carcinoma, Hepatocellular
G
 View
107 20175782 C219A
C
Core
Carcinoma, Hepatocellular
G
 View
108 20170366 F130L
C
Core
HCV Infection
G
S
C
 View
109 20170366 G161S
C
Core
HCV Infection
G
S
C
 View
110 21569441 R70P
C
Core
HCV Infection
G
S
L
 View
111 21569441 R70Q
C
Core
HCV Infection
G
S
L
 View
112 20175782 C378A
C
Core
Carcinoma, Hepatocellular
G
 View
113 20175782 G161S
C
Core
Carcinoma, Hepatocellular
G
 View
114 20175782 G209A
C
Core
Carcinoma, Hepatocellular
G
 View
115 28753979 C91L
C
Core
HCV Infection
View
116 28753979 M91C
C
Core
HCV Infection
View
117 28753979 M91L
C
Core
HCV Infection
View
118 28753979 P70Q
C
Core
HCV Infection
View
119 28753979 P70R
C
Core
HCV Infection
View
120 28753979 R70P
C
Core
HCV Infection
View
121 28753979 R70Q
C
Core
HCV Infection
View
122 28753979 R70W
C
Core
HCV Infection
View
123 20175782 G435A
C
Core
Carcinoma, Hepatocellular
G
 View
Contents
Description

The table shows all curated mutation sites of HCV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.