All Curated Mutation Sites in HCV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HCV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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Click the button below to quickly view the viral genes/regions/protein for mutation

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5'UTR
  
C
  
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p7
  
Protease
  

Keyword: E2
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 19088272 D535A
E2
E2
Carcinoma, Hepatocellular
T
View
2 28758632 G397A
E2
E2
HCV Infection
View
3 28758632 L402F
E2
E2
HCV Infection
View
4 28758632 M405T
E2
E2
HCV Infection
View
5 28758632 S391A
E2
E2
HCV Infection
View
6 20886100 I31T
E2
E2
HCV Infection
S
View
7 20886100 T33A
E2
E2
HCV Infection
S
View
8 20926639 N415D
E2
E2
HCV Infection
View
9 21829654 T563I
E2
E2
HCV Infection
View
10 21912520 G483D
E2
E2
HCV Infection
R
View
11 21912520 T542I
E2
E2
HCV Infection
R
View
12 21912520 T543A
E2
E2
HCV Infection
R
View
13 21912520 Y443H
E2
E2
HCV Infection
R
View
14 21912520 Y443I
E2
E2
HCV Infection
R
View
15 22545104 V719G
E2
E2
HCV Infection
View
16 23696737 N448Q
E2
E2
HCV Infection
View
17 23940646 I599V
E2
E2
HCV Infection
View
18 28758632 R384G
E2
E2
HCV Infection
View
19 19052239 E655G
E2
E2
HCV Infection
G
View
20 19052239 N415Y
E2
E2
HCV Infection
G
View
21 19171049 R614A
E2
E2
HCV Infection
G
View
22 19302336 C281A
E2
E2
HCV Infection
G
View
23 19302336 G278A
E2
E2
HCV Infection
G
View
24 19302336 G278P
E2
E2
HCV Infection
G
View
25 19302336 L271A
E2
E2
HCV Infection
G
View
26 19302336 L280V
E2
E2
HCV Infection
G
View
27 34280245 L388T
E2
E2
Cell line
View
28 34280245 R386H
E2
E2
Cell line
View
29 34280245 S393G
E2
E2
Cell line
View
30 34280245 T385A
E2
E2
Cell line
View
31 34280245 T385I
E2
E2
Cell line
View
32 24990994 V514A
E2
E2
Cell line
View
33 24990994 V515A
E2
E2
Cell line
View
34 24990994 Y507L
E2
E2
Cell line
View
35 25043937 N417S
E2
E2
Cell line
R
View
36 29467319 N415G
E2
E2
Cell line
View
37 29467319 N415S
E2
E2
Cell line
View
38 29467319 N415T
E2
E2
Cell line
View
39 29599605 D657G
E2
E2
Cell line
View
40 34280245 F438V
E2
E2
Cell line
View
41 34280245 F447I
E2
E2
Cell line
View
42 19088272 W529A
E2
E2
Carcinoma, Hepatocellular
T
View
43 34280245 F447L
E2
E2
Cell line
View
44 34280245 F447V
E2
E2
Cell line
View
45 34280245 N417S
E2
E2
Cell line
View
46 34280245 S478G
E2
E2
Cell line
View
47 34280245 T434P
E2
E2
Cell line
View
48 34280245 V710F
E2
E2
Cell line
View
49 34280245 V710L
E2
E2
Cell line
View
50 35763545 F437L
E2
E2
Cell line
G
View
51 35763545 H202Y
E2
E2
Cell line
G
View
52 35763545 Q434R
E2
E2
Cell line
G
View
53 35763545 V719L
E2
E2
Cell line
G
View
54 36424447 A464D
E2
E2
Cell line
View
55 36424447 I414T
E2
E2
Cell line
View
56 36424447 M706L
E2
E2
Cell line
View
57 36424447 V392A
E2
E2
Cell line
View
58 36424447 V402A
E2
E2
Cell line
View
59 36424447 V724I
E2
E2
Cell line
View
60 36424447 Y443H
E2
E2
Cell line
View
61 27345289 N415K
E2
E2
Cell line
I
View
62 24625789 C564W
E2
E2
Cell line
View
63 24625789 C569R
E2
E2
Cell line
View
64 24625789 D481E
E2
E2
Cell line
View
65 24625789 D520G
E2
E2
Cell line
View
66 24625789 D610G
E2
E2
Cell line
View
67 24625789 D698G
E2
E2
Cell line
View
68 24625789 E533G
E2
E2
Cell line
View
69 24625789 E591G
E2
E2
Cell line
View
70 24625789 E650G
E2
E2
Cell line
View
71 24625789 F447L
E2
E2
Cell line
View
72 24625789 F679L
E2
E2
Cell line
View
73 24625789 G436E
E2
E2
Cell line
View
74 24625789 G523S
E2
E2
Cell line
View
75 18712792 N397S
E2
E2
HCV Infection
G
View
76 24625789 I411V
E2
E2
Cell line
View
77 24625789 I414T
E2
E2
Cell line
View
78 24625789 I422T
E2
E2
Cell line
View
79 24625789 I462A
E2
E2
Cell line
View
80 24625789 I462V
E2
E2
Cell line
View
81 24625789 K410E
E2
E2
Cell line
View
82 24625789 K562E
E2
E2
Cell line
View
83 24625789 L427P
E2
E2
Cell line
View
84 24625789 L603M
E2
E2
Cell line
View
85 24625789 L692P
E2
E2
Cell line
View
86 24625789 M456T
E2
E2
Cell line
View
87 24625789 M631T
E2
E2
Cell line
View
88 24625789 N417D
E2
E2
Cell line
View
89 24625789 N428D
E2
E2
Cell line
View
90 24625789 N532G
E2
E2
Cell line
View
91 24625789 N556S
E2
E2
Cell line
View
92 24625789 N623S
E2
E2
Cell line
View
93 24625789 Q467H
E2
E2
Cell line
View
94 24625789 R386C
E2
E2
Cell line
View
95 24625789 R386H
E2
E2
Cell line
View
96 24625789 R424G
E2
E2
Cell line
View
97 24625789 R483G
E2
E2
Cell line
View
98 24625789 R614G
E2
E2
Cell line
View
99 24625789 S419R
E2
E2
Cell line
View
100 24625789 S449L
E2
E2
Cell line
View
101 24625789 S449P
E2
E2
Cell line
View
102 20624431 R445K
E2
E2
HCV Infection
D
G
R
S
View
103 20624431 S747T
E2
E2
HCV Infection
D
G
R
S
View
104 24625789 S663G
E2
E2
Cell line
View
105 24625789 S668P
E2
E2
Cell line
View
106 24625789 T561S
E2
E2
Cell line
View
107 24625789 T563M
E2
E2
Cell line
View
108 25122476 N417S
E2
E2
HCV Infection
I
View
109 25122476 N417T
E2
E2
HCV Infection
I
View
110 25122476 N434D
E2
E2
HCV Infection
I
View
111 25122476 K610R
E2
E2
HCV Infection
I
View
112 25122476 S419N
E2
E2
HCV Infection
I
View
113 25122476 N419S
E2
E2
HCV Infection
I
View
114 25122476 L413I
E2
E2
HCV Infection
I
View
115 24625789 V514G
E2
E2
Cell line
View
116 24625789 V609I
E2
E2
Cell line
View
117 24625789 V699A
E2
E2
Cell line
View
118 24625789 V709A
E2
E2
Cell line
View
119 24625789 V710A
E2
E2
Cell line
View
120 24625789 V710I
E2
E2
Cell line
View
121 24956119 N415D
E2
E2
Hepatitis C, Chronic
D
I
L
View
122 24956119 N415K
E2
E2
Hepatitis C, Chronic
D
I
L
View
123 24956119 N415S
E2
E2
Hepatitis C, Chronic
D
I
L
View
124 24956119 N417S
E2
E2
Hepatitis C, Chronic
D
I
L
View
125 24625789 V712A
E2
E2
Cell line
View
126 24625789 V731A
E2
E2
Cell line
View
127 24625789 W616R
E2
E2
Cell line
View
128 24625789 W736R
E2
E2
Cell line
View
129 24625789 Y611C
E2
E2
Cell line
View
130 29467319 N415D
E2
E2
Cell line
D
G
I
View
131 29467319 N417S
E2
E2
Cell line
D
G
I
View
132 29467319 H386R
E2
E2
Cell line
D
G
I
View
Contents
Description

The table shows all curated mutation sites of HCV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.