All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: NS3

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	35733956	G76S	NS3	ORF3a		R	View
2	33391880	A54V	NS3	ORF3a	COVID-19	G R S L	View
3	33391880	A99S	NS3	ORF3a	COVID-19	G R S L	View
4	33391880	Q57H	NS3	ORF3a	COVID-19	G R S L	View
5	35208920	G251V	NS3	ORF3a	COVID-19	G R L	View
6	33477951	Q57H	NS3	ORF3a	COVID-19	G R S L	View
7	35128118	Q57H	NS3	ORF3a	COVID-19	G R L	View
8	35156767	S26L	NS3	ORF3a	COVID-19	G	View
9	36590492	S26L	NS3	ORF3a	COVID-19	G R S L	View
10	37799539	Q57H	NS3	ORF3a	COVID-19	G R C L	View
11	35215992	G26144T	NS3	ORF3a	COVID-19	G R L	View
12	35215992	G251V	NS3	ORF3a	COVID-19	G R L	View
13	36819024	Q57H	NS3	ORF3a	COVID-19	L	View
14	36819024	G254X	NS3	ORF3a	COVID-19	L	View
15	36504602	D155H	NS3	ORF3a	COVID-19	C L	View
16	36504602	Q57H	NS3	ORF3a	COVID-19	C L	View
17	36504602	S220I	NS3	ORF3a	COVID-19	C L	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.