All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: NSP14
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39048693 R212S
NSP14
ORF1b
Cell line
R
L
View
2 39048693 E453D
NSP14
ORF1b
Cell line
R
L
View
3 39048693 T524I
NSP14
ORF1b
Cell line
R
L
View
4 39048693 A18675C
NSP14
ORF1b
Cell line
R
L
View
5 39048693 G19398T
NSP14
ORF1b
Cell line
R
L
View
6 39048693 C19610T
NSP14
ORF1b
Cell line
R
L
View
7 39047088 I87V
NSP14
ORF1b
Cell line
R
S
View
8 36539656 T31I
NSP14
ORF1b
Cell line
S
L
View
9 36331143 P412H
NSP14
ORF1b

G
View
10 35658876 A394V
NSP14
ORF1b

G
S
L
View
11 36331143 A394V
NSP14
ORF1b

G
View
12 36331143 P46L
NSP14
ORF1b

G
View
13 36331143 L157F
NSP14
ORF1b

G
View
14 36331143 I42V
NSP14
ORF1b

G
View
15 35733956 A274S
NSP14
ORF1b

G
R
View
16 36331143 V381L
NSP14
ORF1b

G
View
17 36512569 C19164T
NSP14
ORF1b

G
R
L
View
18 36512569 D375D
NSP14
ORF1b

G
R
L
View
19 36331143 D243A
NSP14
ORF1b

View
20 36331143 D353A
NSP14
ORF1b

View
21 36331143 D353T
NSP14
ORF1b

View
22 36331143 F368L
NSP14
ORF1b

View
23 36331143 F368N
NSP14
ORF1b

View
24 36331143 W293F
NSP14
ORF1b

View
25 35628343 R391C
NSP14
ORF1b

View
26 36474856 I42V
NSP14
ORF1b
COVID-19
G
R
View
27 36474856 A18163G
NSP14
ORF1b
COVID-19
G
R
View
28 35966679 A394V
NSP14
ORF1b
COVID-19
G
L
View
29 36590492 A394V
NSP14
ORF1b
COVID-19
G
R
S
L
View
30 37243279 A85S
NSP14
ORF1b
COVID-19
G
R
S
C
L
View
31 37224159 A18163G
NSP14
ORF1b
COVID-19
G
R
L
View
32 37224159 G18583A
NSP14
ORF1b
COVID-19
G
R
L
View
33 37224159 I42V
NSP14
ORF1b
COVID-19
G
R
L
View
34 37224159 V182I
NSP14
ORF1b
COVID-19
G
R
L
View
35 37529147 I42V
NSP14
ORF1b
COVID-19
G
R
S
L
View
36 36687433 S434G
NSP14
ORF1b
COVID-19
G
R
S
L
View
37 35966679 P412H
NSP14
ORF1b
COVID-19
G
L
View
38 35966679 P43L
NSP14
ORF1b
COVID-19
G
L
View
39 36778569 Y447H
NSP14
ORF1b
COVID-19
G
R
S
L
View
40 39604601 R163C
NSP14
ORF1b
COVID-19
G
L
View
41 35992703 A353T
NSP14
ORF1b
COVID-19
G
L
View
42 35992703 T372I
NSP14
ORF1b
COVID-19
G
L
View
43 35992703 D496Y
NSP14
ORF1b
COVID-19
G
L
View
44 35992703 D345Y
NSP14
ORF1b
COVID-19
G
L
View
45 38605705 T18087A
NSP14
ORF1b
COVID-19
G
R
S
C
L
View
46 38605705 A18163G
NSP14
ORF1b
COVID-19
G
R
S
C
L
View
47 38605705 I42V
NSP14
ORF1b
COVID-19
G
R
S
C
L
View
48 40100755 I42V
NSP14
ORF1b
COVID-19
View
49 36090111 A1918V
NSP14
ORF1b
COVID-19
R
C
L
View
50 36090111 G1568G
NSP14
ORF1b
COVID-19
R
C
L
View
51 36090111 L1804L
NSP14
ORF1b
COVID-19
R
C
L
View
52 36090111 R1502K
NSP14
ORF1b
COVID-19
R
C
L
View
53 36811085 P203L
NSP14
ORF1b
COVID-19
View
54 36841805 A394V
NSP14
ORF1b
COVID-19
R
View
55 35759503 A1918V
NSP14
ORF1b
COVID-19
R
L
View
56 35743837 A320V
NSP14
ORF1b
COVID-19
R
View
57 34011679 C8626T
NSP14
ORF1b
COVID-19
R
View
58 34011679 C18452T
NSP14
ORF1b
COVID-19
R
View
59 32793182 C18060T
NSP14
ORF1b
COVID-19
R
View
60 36819024 Q168H
NSP14
ORF1b
COVID-19
L
View
61 36819024 M169V
NSP14
ORF1b
COVID-19
L
View
62 36819024 S171X
NSP14
ORF1b
COVID-19
L
View
63 36819024 D172H
NSP14
ORF1b
COVID-19
L
View
64 36819024 L174X
NSP14
ORF1b
COVID-19
L
View
65 36819024 N176S
NSP14
ORF1b
COVID-19
L
View
66 36819024 A394V
NSP14
ORF1b
COVID-19
L
View
67 38435775 I42V
NSP14
ORF1b
COVID-19
C
L
View
68 38435775 A394V
NSP14
ORF1b
COVID-19
C
L
View
69 40358207 D222Y
NSP14
ORF1b
Cell line
G
View
70 39660912 I42V
NSP14
ORF1b
Cell line
G
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.