All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: NSP15

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	39932973	G247V	NSP15	ORF1b	Cell line		View
2	39932973	G248V	NSP15	ORF1b	Cell line		View
3	39932973	H249A	NSP15	ORF1b	Cell line		View
4	39932973	H249Y	NSP15	ORF1b	Cell line		View
5	39932973	H250A	NSP15	ORF1b	Cell line		View
6	39932973	H250Y	NSP15	ORF1b	Cell line		View
7	39932973	K60R	NSP15	ORF1b	Cell line		View
8	39932973	T66I	NSP15	ORF1b	Cell line		View
9	39048693	E21A	NSP15	ORF1b	Cell line	R L	View
10	39048693	A19682C	NSP15	ORF1b	Cell line	R L	View
11	35547225	T2165M	NSP15	ORF1b		G S L	View
12	35547225	P2256S	NSP15	ORF1b		G S L	View
13	35658876	V303F	NSP15	ORF1b		S L	View
14	37224159	C19955T	NSP15	ORF1b	COVID-19	G R L	View
15	37224159	A20055G	NSP15	ORF1b	COVID-19	G R L	View
16	37224159	E145E	NSP15	ORF1b	COVID-19	G R L	View
17	37224159	T1121I	NSP15	ORF1b	COVID-19	G R L	View
18	37224159	T112I	NSP15	ORF1b	COVID-19	G R L	View
19	37529147	T112I	NSP15	ORF1b	COVID-19	G R S L	View
20	35992703	T105I	NSP15	ORF1b	COVID-19	G L	View
21	38605705	C19955T	NSP15	ORF1b	COVID-19	G R S C L	View
22	38605705	A20055G	NSP15	ORF1b	COVID-19	G R S C L	View
23	38605705	T2163I	NSP15	ORF1b	COVID-19	G R S C L	View
24	36841805	T112I	NSP15	ORF1b	COVID-19	R	View
25	33384909	A6544T	NSP15	ORF1b	COVID-19	R	View
26	38348230	V236I	NSP15	ORF1b	COVID-19	C L	View
27	39861827	A20268G	NSP15	ORF1b	COVID-19	R L	View
28	33558859	D335N	NSP15	ORF1b	COVID-19	R L	View
29	32793182	A20268G	NSP15	ORF1b	COVID-19	R	View
30	38435775	T112I	NSP15	ORF1b	COVID-19	C L	View
31	38435775	S147G	NSP15	ORF1b	COVID-19	C L	View
32	38435775	F329L	NSP15	ORF1b	COVID-19	C L	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.