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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19 Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	39048693	F529L	NSP2	ORF1a	Cell line	R L	View
2	39048693	T2392A	NSP2	ORF1a	Cell line	R L	View
3	35547225	F343L	NSP2	ORF1a		G S L	View
4	35547225	P732S	NSP2	ORF1a		G S L	View
5	35733956	T85I	NSP2	ORF1a		G R	View
6	36512569	C913T	NSP2	ORF1a		G R L	View
7	36512569	A1643T	NSP2	ORF1a		G R L	View
8	36512569	C2395T	NSP2	ORF1a		G R L	View
9	36512569	C2453T	NSP2	ORF1a		G R L	View
10	36512569	S36S	NSP2	ORF1a		G R L	View
11	36512569	N280Y	NSP2	ORF1a		G R L	View
12	36512569	V530V	NSP2	ORF1a		G R L	View
13	36512569	L550F	NSP2	ORF1a		G R L	View
14	36686884	S232S	NSP2	ORF1a		R L	View
15	36686884	S232P	NSP2	ORF1a		R L	View
16	38605705	G1085T	NSP2	ORF1a	COVID-19	G R S C L	View
17	38605705	V94L	NSP2	ORF1a	COVID-19	G R S C L	View
18	37224159	C2710T	NSP2	ORF1a	COVID-19	G R L	View
19	37224159	L635L	NSP2	ORF1a	COVID-19	G R L	View
20	37243279	H208Y	NSP2	ORF1a	COVID-19	G R S C L	View
21	32823907	K489E	NSP2	ORF1a	COVID-19	G R S L	View
22	35992703	T388I	NSP2	ORF1a	COVID-19	G L	View
23	35992703	S36N	NSP2	ORF1a	COVID-19	G L	View
24	35992703	K67N	NSP2	ORF1a	COVID-19	G L	View
25	35992703	A26V	NSP2	ORF1a	COVID-19	G L	View
26	35992703	T439A	NSP2	ORF1a	COVID-19	G L	View
27	35371558	K81N	NSP2	ORF1a	COVID-19	G L	View
28	35605880	I349V	NSP2	ORF1a	COVID-19	G R L	View
29	39604601	E264G	NSP2	ORF1a	COVID-19	G L	View
30	34547443	T85I	NSP2	ORF1a	COVID-19	G R	View
31	33920487	T85I	NSP2	ORF1a	COVID-19	G R	View
32	33572190	I120F	NSP2	ORF1a	COVID-19	G R L	View
33	33572190	A1163T	NSP2	ORF1a	COVID-19	G R L	View
34	34547443	G339C	NSP2	ORF1a	COVID-19	G R L	View
35	34547443	G339S	NSP2	ORF1a	COVID-19	G R L	View
36	32742035	448delD	NSP2	ORF1a	COVID-19	R	View
37	32742035	G392D	NSP2	ORF1a	COVID-19	R	View
38	38605705	C925T	NSP2	ORF1a	COVID-19	G R S C L	View
39	38605705	C1627T	NSP2	ORF1a	COVID-19	G R S C L	View
40	38605705	C2710T	NSP2	ORF1a	COVID-19	G R S C L	View
41	32595352	C1059T	NSP2	ORF1a	COVID-19	R	View
42	32595352	T266I	NSP2	ORF1a	COVID-19	R	View
43	36090111	G411G	NSP2	ORF1a	COVID-19	R C L	View
44	36090111	G514G	NSP2	ORF1a	COVID-19	R C L	View
45	36090111	G519S	NSP2	ORF1a	COVID-19	R C L	View
46	36090111	L730F	NSP2	ORF1a	COVID-19	R C L	View
47	36090111	N189N	NSP2	ORF1a	COVID-19	R C L	View
48	36090111	S216S	NSP2	ORF1a	COVID-19	R C L	View
49	36841805	T85I	NSP2	ORF1a	COVID-19	R	View
50	35614572	A192V	NSP2	ORF1a	COVID-19	R	View
51	35614572	R218C	NSP2	ORF1a	COVID-19	R	View
52	35614572	T85I	NSP2	ORF1a	COVID-19	R	View
53	35913920	268delD	NSP2	ORF1a	COVID-19	R	View
54	35913920	I559V	NSP2	ORF1a	COVID-19	R	View
55	35913920	P585S	NSP2	ORF1a	COVID-19	R	View
56	35913920	T85I	NSP2	ORF1a	COVID-19	R	View
57	32972934	G339S	NSP2	ORF1a	COVID-19	S L	View
58	32972934	I120F	NSP2	ORF1a	COVID-19	S L	View
59	32972934	V480I	NSP2	ORF1a	COVID-19	S L	View
60	33384909	A372V	NSP2	ORF1a	COVID-19	R	View
61	33384909	A405T	NSP2	ORF1a	COVID-19	R	View
62	33384909	E352Q	NSP2	ORF1a	COVID-19	R	View
63	33384909	E743V	NSP2	ORF1a	COVID-19	R	View
64	33384909	H388Y	NSP2	ORF1a	COVID-19	R	View
65	33384909	R398C	NSP2	ORF1a	COVID-19	R	View
66	35891618	G265V	NSP2	ORF1a	COVID-19	S L	View
67	35891618	T85I	NSP2	ORF1a	COVID-19	S L	View
68	38348230	L451L	NSP2	ORF1a	COVID-19	C L	View
69	37529147	L274L	NSP2	ORF1a	COVID-19	R S L	View
70	33347622	V198I	NSP2	ORF1a	COVID-19		View
71	34419925	S512Y	NSP2	ORF1a	COVID-19	L	View
72	32793182	T85I	NSP2	ORF1a	COVID-19	R	View
73	32793182	P585S	NSP2	ORF1a	COVID-19	R	View
74	32793182	I599V	NSP2	ORF1a	COVID-19	R	View
75	33163695	I120F	NSP2	ORF1a	COVID-19	R L	View
76	33184173	C1059T	NSP2	ORF1a	COVID-19		View
77	33184173	T265I	NSP2	ORF1a	COVID-19		View
78	33357233	P91S	NSP2	ORF1a	COVID-19	R	View
79	33357233	T85I	NSP2	ORF1a	COVID-19	R	View
80	33357233	V198I	NSP2	ORF1a	COVID-19	R	View
81	33760807	T85I	NSP2	ORF1a	COVID-19	R S L	View
82	33920487	I120F	NSP2	ORF1a	COVID-19	R	View
83	38483913	P129L	NSP2	ORF1a	COVID-19	L	View
84	38435775	A205S	NSP2	ORF1a	COVID-19	C L	View
85	38435775	E457K	NSP2	ORF1a	COVID-19	C L	View
86	38435775	G517V	NSP2	ORF1a	COVID-19	C L	View
87	38028396	G262V	NSP2	ORF1a	COVID-19	R C L	View
88	38028396	G392D	NSP2	ORF1a	COVID-19	R C L	View
89	38028396	I431M	NSP2	ORF1a	COVID-19	R C L	View
90	38028396	K337D	NSP2	ORF1a	COVID-19	R C L	View
91	38028396	N348S	NSP2	ORF1a	COVID-19	R C L	View
92	38028396	R207C	NSP2	ORF1a	COVID-19	R C L	View
93	38028396	T224I	NSP2	ORF1a	COVID-19	R C L	View
94	38028396	T265I	NSP2	ORF1a	COVID-19	R C L	View
95	36786950	T223I	NSP2	ORF1a	COVID-19	R S C L	View
96	36504602	L217V	NSP2	ORF1a	COVID-19	C L	View
97	32595354	V198I	NSP2	ORF1a	COVID-19	R L	View
98	32595354	R27C	NSP2	ORF1a	COVID-19	R L	View