All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: NSP5

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	40062859	A393G	NSP5	ORF1a	Cell line		View
2	40062859	A395C	NSP5	ORF1a	Cell line		View
3	40062859	C561T	NSP5	ORF1a	Cell line		View
4	40062859	F230L	NSP5	ORF1a	Cell line		View
5	40062859	H132P	NSP5	ORF1a	Cell line		View
6	40062859	P132H	NSP5	ORF1a	Cell line		View
7	33907518	G15S	NSP5	ORF1a	Cell line		View
8	33907518	K90R	NSP5	ORF1a	Cell line		View
9	39048693	T21I	NSP5	ORF1a	Cell line	R L	View
10	39048693	C10116T	NSP5	ORF1a	Cell line	R L	View
11	39584063	C145A	NSP5	ORF1a		R	View
12	39584063	C145S	NSP5	ORF1a		R	View
13	39584063	G15S	NSP5	ORF1a		R	View
14	39584063	H41A	NSP5	ORF1a		R	View
15	39584063	H41D	NSP5	ORF1a		R	View
16	39584063	H41E	NSP5	ORF1a		R	View
17	39584063	K90R	NSP5	ORF1a		R	View
18	39584063	L89F	NSP5	ORF1a		R	View
19	39584063	T21I	NSP5	ORF1a		R	View
20	35628343	P132H	NSP5	ORF1a		G	View
21	35389264	A46S	NSP5	ORF1a		R	View
22	35389264	S46A	NSP5	ORF1a		R	View
23	36686884	I78N	NSP5	ORF1a		R L	View
24	38276171	P132H	NSP5	ORF1a	COVID-19	G R S L	View
25	36474856	P132H	NSP5	ORF1a	COVID-19	G R	View
26	33391880	M49I	NSP5	ORF1a	COVID-19	G R S L	View
27	38276171	V186F	NSP5	ORF1a	COVID-19	G R S L	View
28	37086978	K90R	NSP5	ORF1a	COVID-19	G R	View
29	36474856	K90R	NSP5	ORF1a	COVID-19	G R	View
30	37224159	C10198T	NSP5	ORF1a	COVID-19	G R L	View
31	37224159	G10447A	NSP5	ORF1a	COVID-19	G R L	View
32	37224159	C10449A	NSP5	ORF1a	COVID-19	G R L	View
33	37224159	D48D	NSP5	ORF1a	COVID-19	G R L	View
34	37224159	P132H	NSP5	ORF1a	COVID-19	G R L	View
35	37224159	R131R	NSP5	ORF1a	COVID-19	G R L	View
36	37086978	P132H	NSP5	ORF1a	COVID-19	G R	View
37	37630656	L24F	NSP5	ORF1a	COVID-19	G R S C	View
38	35966679	P108S	NSP5	ORF1a	COVID-19	G L	View
39	35992703	A260V	NSP5	ORF1a	COVID-19	G L	View
40	36474856	G71S	NSP5	ORF1a	COVID-19	G R	View
41	38605705	C10198T	NSP5	ORF1a	COVID-19	G R S C L	View
42	38605705	G10447A	NSP5	ORF1a	COVID-19	G R S C L	View
43	38605705	C10449A	NSP5	ORF1a	COVID-19	G R S C L	View
44	38605705	P132H	NSP5	ORF1a	COVID-19	G R S C L	View
45	38276171	K90R	NSP5	ORF1a	COVID-19	R S L	View
46	34678071	P252L	NSP5	ORF1a	COVID-19		View
47	36008511	A3529T	NSP5	ORF1a	COVID-19	R C L	View
48	36008511	G3278S	NSP5	ORF1a	COVID-19	R C L	View
49	36090111	A3209V	NSP5	ORF1a	COVID-19	R C L	View
50	36090111	T3255I	NSP5	ORF1a	COVID-19	R C L	View
51	35707000	C10376T	NSP5	ORF1a	COVID-19	R	View
52	35707000	P108S	NSP5	ORF1a	COVID-19	R	View
53	35913920	G15S	NSP5	ORF1a	COVID-19	R	View
54	33384909	I3512T	NSP5	ORF1a	COVID-19	R	View
55	33384909	I3522V	NSP5	ORF1a	COVID-19	R	View
56	36672914	P132H	NSP5	ORF1a	COVID-19	C L	View
57	37529147	D48D	NSP5	ORF1a	COVID-19	R S L	View
58	37529147	P132H	NSP5	ORF1a	COVID-19	R S L	View
59	37529147	R131R	NSP5	ORF1a	COVID-19	R S L	View
60	39294134	A173T	NSP5	ORF1a	COVID-19	D R S C L	View
61	39294134	G283C	NSP5	ORF1a	COVID-19	R S C L	View
62	39294134	M165I	NSP5	ORF1a	COVID-19	R S C L	View
63	39294134	T169I	NSP5	ORF1a	COVID-19	D R S C L	View
64	32793182	G15S	NSP5	ORF1a	COVID-19	R	View
65	34876891	A7V	NSP5	ORF1a	COVID-19	R L	View
66	34876891	C22N	NSP5	ORF1a	COVID-19	R L	View
67	34876891	H246Y	NSP5	ORF1a	COVID-19	R L	View
68	34876891	I43V	NSP5	ORF1a	COVID-19	R L	View
69	34876891	K236R	NSP5	ORF1a	COVID-19	R L	View
70	34876891	K90R	NSP5	ORF1a	COVID-19	R L	View
71	34876891	L75F	NSP5	ORF1a	COVID-19	R L	View
72	34876891	N142L	NSP5	ORF1a	COVID-19	R L	View
73	38276171	A191V	NSP5	ORF1a	COVID-19	R S L	View
74	38435775	G283S	NSP5	ORF1a	COVID-19	C L	View
75	38435775	P132H	NSP5	ORF1a	COVID-19	C L	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.