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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19 Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	35624123	C11572T	NSP6	ORF1a		R	View
2	38293247	F35G	NSP6	ORF1a		R I T	View
3	38293247	I162T	NSP6	ORF1a		R I T	View
4	38293247	L125F	NSP6	ORF1a		R I T	View
5	38293247	L37F	NSP6	ORF1a		R I T	View
6	38293247	A88V	NSP6	ORF1a		R	View
7	38293247	F108L	NSP6	ORF1a		R	View
8	38293247	G107S	NSP6	ORF1a		R	View
9	38293247	M183I	NSP6	ORF1a		R	View
10	38293247	S106T	NSP6	ORF1a		R	View
11	38293247	T17I	NSP6	ORF1a		R	View
12	38293247	V120L	NSP6	ORF1a		R	View
13	38293247	V149F	NSP6	ORF1a		R	View
14	38293247	Y153F	NSP6	ORF1a		R	View
15	38293247	L22I	NSP6	ORF1a		R	View
16	38293247	V190F	NSP6	ORF1a		R	View
17	36686884	F251L	NSP6	ORF1a		R L	View
18	36686884	F251F	NSP6	ORF1a		R L	View
19	35617193	108delF	NSP6	ORF1a		S L	View
20	35966679	T77A	NSP6	ORF1a	COVID-19	G L	View
21	36590492	T77A	NSP6	ORF1a	COVID-19	G R S L	View
22	33170902	L3606F	NSP6	ORF1a	COVID-19	G R L	View
23	40163530	L260F	NSP6	ORF1a	COVID-19	G L	View
24	37224159	C11224T	NSP6	ORF1a	COVID-19	G R L	View
25	37224159	T11288A	NSP6	ORF1a	COVID-19	G R L	View
26	37224159	G11291A	NSP6	ORF1a	COVID-19	G R L	View
27	37224159	T11296G	NSP6	ORF1a	COVID-19	G R L	View
28	37224159	F108L	NSP6	ORF1a	COVID-19	G R L	View
29	37224159	G107S	NSP6	ORF1a	COVID-19	G R L	View
30	37224159	106delS	NSP6	ORF1a	COVID-19	G R L	View
31	37224159	S106T	NSP6	ORF1a	COVID-19	G R L	View
32	37224159	V84V	NSP6	ORF1a	COVID-19	G R L	View
33	34678071	D156G	NSP6	ORF1a	COVID-19	G	View
34	36778569	S106F	NSP6	ORF1a	COVID-19	G R S L	View
35	35215992	G11083T	NSP6	ORF1a	COVID-19	G R L	View
36	35215992	L37F	NSP6	ORF1a	COVID-19	G R L	View
37	35992703	Q208H	NSP6	ORF1a	COVID-19	G L	View
38	35966679	106delS	NSP6	ORF1a	COVID-19	G L	View
39	35966679	107delG	NSP6	ORF1a	COVID-19	G L	View
40	35966679	108delF	NSP6	ORF1a	COVID-19	G L	View
41	32742035	L3606F	NSP6	ORF1a	COVID-19	R	View
42	32742035	L37F	NSP6	ORF1a	COVID-19	R	View
43	38605705	G11266T	NSP6	ORF1a	COVID-19	G R S C L	View
44	38605705	G11365T	NSP6	ORF1a	COVID-19	G R S C L	View
45	38605705	C11824T	NSP6	ORF1a	COVID-19	G R S C L	View
46	38605705	L98F	NSP6	ORF1a	COVID-19	G R S C L	View
47	38605705	106delS	NSP6	ORF1a	COVID-19	G R S C L	View
48	38605705	107delG	NSP6	ORF1a	COVID-19	G R S C L	View
49	38605705	108delF	NSP6	ORF1a	COVID-19	G R S C L	View
50	32595352	G11083T	NSP6	ORF1a	COVID-19	R	View
51	32595352	L36F	NSP6	ORF1a	COVID-19	R	View
52	39774959	S106T	NSP6	ORF1a	COVID-19		View
53	34678071	L257F	NSP6	ORF1a	COVID-19		View
54	36008511	L3691S	NSP6	ORF1a	COVID-19	R C L	View
55	36090111	3677delF	NSP6	ORF1a	COVID-19	R C L	View
56	36090111	3676delG	NSP6	ORF1a	COVID-19	R C L	View
57	36090111	L3667L	NSP6	ORF1a	COVID-19	R C L	View
58	36090111	3675delS	NSP6	ORF1a	COVID-19	R C L	View
59	36090111	T3646A	NSP6	ORF1a	COVID-19	R C L	View
60	36090111	T3750I	NSP6	ORF1a	COVID-19	R C L	View
61	36090111	V3690V	NSP6	ORF1a	COVID-19	R C L	View
62	36090111	V3718A	NSP6	ORF1a	COVID-19	R C L	View
63	36841805	T77A	NSP6	ORF1a	COVID-19	R	View
64	36877070	38insF	NSP6	ORF1a	COVID-19		View
65	35707124	L75F	NSP6	ORF1a	COVID-19	R L	View
66	35707124	V149F	NSP6	ORF1a	COVID-19	R L	View
67	35759503	T3646A	NSP6	ORF1a	COVID-19	R L	View
68	35913920	L37F	NSP6	ORF1a	COVID-19	R	View
69	33496683	G11083T	NSP6	ORF1a	COVID-19	R L	View
70	33496683	L37F	NSP6	ORF1a	COVID-19	R L	View
71	36672914	Y234H	NSP6	ORF1a	COVID-19	C L	View
72	36672914	Q208R	NSP6	ORF1a	COVID-19	C L	View
73	36672914	I189V	NSP6	ORF1a	COVID-19	C L	View
74	33219681	L37F	NSP6	ORF1a	COVID-19	R S C L	View
75	33932525	3606 fs L	NSP6	ORF1a	COVID-19	R C L	View
76	34870573	G11083T	NSP6	ORF1a	COVID-19	R	View
77	34997207	L37F	NSP6	ORF1a	COVID-19		View
78	36819024	I199L	NSP6	ORF1a	COVID-19	L	View
79	36819024	I210V	NSP6	ORF1a	COVID-19	L	View
80	36819024	M211L	NSP6	ORF1a	COVID-19	L	View
81	36819024	L212S	NSP6	ORF1a	COVID-19	L	View
82	36819024	V213I	NSP6	ORF1a	COVID-19	L	View
83	36819024	214delY	NSP6	ORF1a	COVID-19	L	View
84	36819024	C215A	NSP6	ORF1a	COVID-19	L	View
85	36819024	F216L	NSP6	ORF1a	COVID-19	L	View
86	36819024	I124V	NSP6	ORF1a	COVID-19	L	View
87	36819024	V149F	NSP6	ORF1a	COVID-19	L	View
88	38483913	V149A	NSP6	ORF1a	COVID-19	L	View
89	38483913	T181I	NSP6	ORF1a	COVID-19	L	View
90	38435775	T77A	NSP6	ORF1a	COVID-19	C L	View
91	38435775	106delS	NSP6	ORF1a	COVID-19	C L	View
92	38435775	107delG	NSP6	ORF1a	COVID-19	C L	View
93	38435775	108delF	NSP6	ORF1a	COVID-19	C L	View
94	38435775	Q208R	NSP6	ORF1a	COVID-19	C L	View
95	36504602	D159G	NSP6	ORF1a	COVID-19	C L	View
96	32595354	L37F	NSP6	ORF1a	COVID-19	R L	View
97	40358207	L260F	NSP6	ORF1a	Cell line	G	View
98	39660912	I189V	NSP6	ORF1a	Cell line	G	View